V. Sesha Raghav

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PURPOSE Valve mediated hemodynamics have been postulated to contribute to pathology of the ascending aorta (AAo). The objective of this study is to assess the association of aortic valve morphology and hemodynamics with downstream AAo size in subjects with bicuspid aortic valve (BAV) disease. MATERIALS AND METHODS Four-dimensional flow MRI at 1.5 or 3(More)
Valve-in-valve transcatheter aortic valve replacement (VIV-TAVR) has proven to be a successful treatment for high risk patients with failing aortic surgical bioprostheses. However, thrombus formation on the leaflets of the valve has emerged as a major issue in such procedures, posing a risk of restenosis, thromboembolism, and reduced durability. In this(More)
BACKGROUND AND AIM OF THE STUDY Transcatheter aortic valve replacements (TAVRs) are performed using fluoroscopic guidance, which makes precise positioning challenging. The aim of the present study was to investigate the effect of TAV positioning on flow characteristics in the ascending aorta and sinuses. METHODS A commonly used TAV design with a(More)
OBJECTIVES The aim of this study was to investigate the hemodynamic performance of a transcatheter heart valve (THV) deployed at different valve-in-valve positions in an in vitro model using a small surgical bioprosthesis. BACKGROUND Patients at high surgical risk with failing 19-mm surgical aortic bioprostheses are not candidates for valve-in-valve(More)
BACKGROUND Durability and hemodynamic performance are top considerations in selecting a valve for valve replacement surgery. This study was conducted in order to evaluate the long-term mechanical durability and hydrodynamic performance of the Carpentier-Edwards PERIMOUNT Magna Ease Bioprostheses, through 1 billion cycles (equivalent to 25 years). METHODS(More)
OBJECTIVES The purpose of this study was to optimize hemodynamic performance of valve-in-valve (VIV) according to transcatheter heart valve (THV) type (balloon vs. self-expandable), size, and deployment positions in an in vitro model. BACKGROUND VIV transcatheter aortic valve replacement is increasingly used for the treatment of patients with a failing(More)
In the last few years, Power Line Communication (PLC) has gained momentum due to high data rate communication over existing power lines. The Home Plug AV (HPAV) and High Definition Power Line Communication (HD-PLC) are PLC specifications designed to provide 200 Mbps of PHY channel rate between hosts connected by modems operating at 2-28 MHz frequency range(More)
The mitral valve (MV) is a bileaflet valve positioned between the left atrium and ventricle of the heart. The annulus of the MV has been observed to undergo geometric changes during the cardiac cycle, transforming from a saddle D-shape during systole to a flat (and less eccentric) D-shape during diastole. Prosthetic MV devices, including heart valves and(More)
Acute aortic regurgitation (AR) post-chronic aortic stenosis is a prevalent phenomenon occurring in patients who undergo transcatheter aortic valve replacement (TAVR) surgery. The objective of this work was to characterize the effects of left ventricular diastolic stiffness (LVDS) and AR severity on LV performance. Three LVDS models were inserted into a(More)