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Light touch and low-frequency vibration sense deteriorate during the development of diabetic neuropathy. As Meissner corpuscles are mechanoreceptors that respond to these sensations, this study explored the structural changes of neurites in Meissner corpuscles of diabetic mice C57BL/Ks(db/db). We evaluated silver impregnated neurites from forepaw digital(More)
Specifically stained features in microscopic images rarely have a unique range of grey levels which would permit selection of the features by simple thresholding. The spaces between features and immediately surrounding them are often as dark or darker than the more lightly stained features. An algorithm for minima equalization which facilitates the(More)
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