V R Mamikonian

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Detailed analysis of copper compounds migration in the corneal stroma are presented. The biochemical conditions of the middle periphery of the cornea is found to inhibit copper ions movement to the center in patients with keratoconus due to increased tear alkalinity. Low concentration of dichlorocuprate (I) ion in the center of cornea results in(More)
In the period after surgical correction of myopia and astigmatism in 30 patients (44 eyes) by radial keratotomy, contrast sensitivity deteriorated slightly. The disturbances, however, were transitory, and the general trend was toward restoration of function. Strict adherence to an adequate operative technique prevented a marked decline in contrast(More)
The results of experimental and clinical trials of a new type of transplantation of the cornea, stromaplasty, have shown the possibility of a blunt detachment from Descemet's membrane and removal of the deep lamellae of recipient's stroma, followed by replacement of the defect with a through allotransplant. Further studies are necessary to validate this(More)
A total of 78 patients (143 eyes) with low, medium and high degree myopia were assessed. Apart from standard ophthalmological tests, flowmetry and duplex ultrasound of ocular vessels were performed in all cases to evaluate volumetric and velocity parameters of ocular blood flow in relation to the length of anterior-posterior axis and the degree of myopia.(More)
The effects of two 5-membered (SP5, SP6) endogenous synthetic peptide fragments of protein S100b on the course of regenerative-reparative processes in the corneas of Wistar rats were morphologically studied after making a graduated injury. Conjunctival or endonasal injection of the peptides was made at two concentrations of 10(-6) and 10(-8) M. The study(More)
The results of keratometry of 13 allotransplants have confirmed the rightfulness of the employed methods for calculation of the parameters of biolenses for epikeratophakia. For clinical application the initial intumescence should be taken into consideration, as well as the donor tissue thickening during its freezing for working on a lathe.
Ultrasound and optical coherent biometries were used to study the influence of the biometric parameters of the anterior segment of the eyeball on the precision of calculation of the focal power of an intraocular lens (IOL). A clinical study has demonstrated that among the biometric parameters of the anterior segment of the eyeball, there is a close(More)
A new form of refractive keratoplasty for the correction of myopia was developed using a new approach to the problem. The midperipheral annular area of the recipient cornea was deepithelialized, and Bowman's layer was removed using a special bore coated with diamond crumbs. A cryolathed annular graft was placed on this prepared midperipheral area of the(More)
The paper presents the results of studying the photofungicidal activity of a photosens (octacationic phthalocyanine) in the in vitro and in vivo systems. Cultured Candida guilliermondii were employed in in vitro investigations. The single combined action of octacationic phthalocyanine at a concentration of up to 1 microM and laser irradiation at a(More)
Eighty volunteer computer operators were examined experimentally under the conditions of working with different-type video monitors, i.e. electron-beam (EB), liquid-crystal (LC), including different visual loads (typing, computer games, and gaze fixation). Experiments lasted for as long as 6 hours. The absolute accommodation volume (AAV), relative(More)