V. P. Varavin

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Oral hypoglycemic drugs related to sulfanilamides and biguanides are widely used for treating the achrestic diabetes, however, they have a number of side effects. For instance, treatment with guanides may be accompanied by lactacidemia, hyperpyruvatemia and dyspepsia reactions [ I ]. The major disadvantages of sulfanilamide therapy are: secondary (induced)(More)
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