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We have recently reported that acute intraperitoneal administration of pyridostigmine bromide to rats resulted in significant decrements in physical performance in the heat, adverse thermoregulatory effects, and exacerbated elevations in several indices of heat/exercise injury. Since it will be consumed orally as a prophylaxis for organophosphate poisoning,(More)
As part of a large-scale field feeding system test we were able to collect and study hundreds of aliquots of overnight urine samples obtained immediately prior to a fasting blood sample on days 1, 20, and 44 of the field test. The large number of experimental samples (greater than 650) and concomitant collection of blood and urine aliquots along with data(More)
The ability of the human eye to detect nitrogen nuclei that enter the retina at speeds just above the Cerenkov threshold has been confirmed in an experiment at the Princeton Particle Accelerator. A system for beam transport and subject alignment delivered individual nitrogen nuclei onto a spot 3 millimeters in diameter on the retina at a visual angle of 7(More)
Exposing the human eye to individual carbon ions (6C+) moving at relativistic speeds results in visual phenomena that include point flashes, streaks, and larger diffuse flashes. The diffuse flashes have previously been observed by astronauts in space but not in laboratory experiments with particles of high atomic number and energy. They are observed only(More)
Visual phenomena in the form of colorless flashes of light were observed by astronauts in deep space when their eyes were closed and adapted to darkness. We describe in this paper laboratory experiments and calculations which indicate that many of these flashes are the result of visible light generated within the astronauts' eyeball in the form of Cerenkov(More)
Astronauts on Apollo and Skylab missions have reported observing a variety of visual phenomena when their eyes were closed and adapted to darkness. These observations were studied under controlled conditions during a number of sessions on board Apollo and Skylab spacecraft and the data available to date on these so-called light flashes are in the form of(More)
We have employed the primed constant infusion technique to investigate the metabolic effects of the organophosphate antidote, atropine, on glucose homeostasis in rats. This method utilizes the radioisotopes 6-3H-glucose to measure production and uptake and U-14C-glucose to measure oxidation. Our data indicate that glucose production significantly (p less(More)