V Lakshmipathi

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ETHNOPHARMACOLOGICAL RELEVANCE Terminalia chebula has an esteemed origin in Indian mythology; its fruits are used to treat many diseases such as digestive, diabetes, colic pain, chronic cough, sore throat, asthma, etc. AIM OF THE STUDY The water or ethanolic extracts of the fruits were reported to have anti-oxidant, anti-inflammatory, anti-cancer and(More)
Gallic acid (GA) induces apoptosis in various cancer cell lines. In this study, we investigated the apoptotic activity induced by GA on chronic myeloid leukemia (CML) cell line-K562 and the underlying mechanism. GA reduced the viability of K562 cells in a dose and time dependent manner. GA led to G0/G1 phase arrest in K562 cells by promoting p21 and p27 and(More)
Disc gel electrophoretic patterns of esterases obtained in the buffer (0.1 M Tris-HCl buffer pH 7.4) extracts of the brains of twelve species belonging to various classes of vertebrates ranging from fishes to mammals are compared. Substrate specificity and inhibitor sensitivity is used to classify the enzymes into different classes of esterases. The pattern(More)
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