V Kamalakkannan

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Candesartan cilexetil (CC) is a newer class of angiotensin II receptor antagonist used for the treatment of hypertension. The solubility of the CC is very poor and its oral bioavailability is only 15%. The controlledrelease polar lipid microparticles of CC (formulations F1, F2, F3 and F4) were prepared using variable erodible lipophilic excipients like(More)
  • V Kamalakkannan, K S G Arul Kumaran, C Kannan, S Bhama, R Sambath Kumar, J K K Nataraja +1 other
  • 2013
Microspheres containing Diltiazem hydrochloride (DTZ Hcl) were prepared with various Polymethacrylates, with different permeability characteristics (Eudragit RSPO and Eudragit RLPO) and also with mixtures of these polymers in a 1:1 and 1:2 ratio using the solvent evaporation method. The aim was to investigate the effects of the permeability of the polymers(More)
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