V. Kamalakkannan

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Candesartan cilexetil (CC) is a newer class of angiotensin II receptor antagonist used for the treatment of hypertension. The solubility of the CC is very poor and its oral bioavailability is only 15%. The controlledrelease polar lipid microparticles of CC (formulations F1, F2, F3 and F4) were prepared using variable erodible lipophilic excipients like(More)
Microspheres containing Diltiazem hydrochloride (DTZ Hcl) were prepared with various Polymethacrylates, with different permeability characteristics (Eudragit RSPO and Eudragit RLPO) and also with mixtures of these polymers in a 1:1 and 1:2 ratio using the solvent evaporation method. The aim was to investigate the effects of the permeability of the polymers(More)
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