V. K. Pozur

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The data are presented on the effect of activation of by peptidoglycans from cell walls of Staphylococcus aureus and Brevibacterium flavum on the DNA synthesis intensity in the mice spleen, thymus and bone marrow in vivo. Maximum of the peptidoglycan influence on the DNA synthesis intensity is observed 12-36 hours after injection. As a rule, higher doses of(More)
Heterogeneity of peptidoglycans of Staphylococcus aureus of strains 3272 and Wood-46, Brevibacterium flavum, Micrococcus lysodeikticus has been studied by the method of electrophoresis in the system polyacrylamide gel--sodium dodecylsulfate. It is shown that peptidoglycans of different strains of S. aureus and other species of gram-positive bacteria treated(More)
By immunoaffinity chromatography using antibodies of a monospecific immune serume it was thus possible to isolate epidermal G2-chalone from an alcoholic extract of skin in one stage. It can evidently be obtained by this method also from an aqueous extract of skin without preliminary fractionation with alcohol, and the whole procedure of purification can be(More)
The results of investigation of the influence of Staphylococcus peptidoglycan on supraoptic (SON) and paraventricular (PVN) hypothalamic nuclei, adrenal and thyroid glands of CBA mice was studied. Alterations in the SON and PVN secretory cells were found. The percentage of neurocytes that actively synthesize and secrete the Gomori [correction of(More)
Modulatory effects of protein A (PA) and peptidoglycan (PG) fromStaphylococcus aureus on the smooth muscle contractions elicited by neurotransmitters were studied. PA and PG were found to suppress the myometrium smooth muscle contractions elicited by acetylcholine applications. The effects of the substances on the contractions were due to non-competitive(More)
The mitogenic effect of corpuscular antigens with respect to the splenocytes of animals was found to depend on the strain of Staphylococcus aureus. The maximum synthesis of DNA in the cells was induced by corpuscular antigen Smith and the minimum synthesis, by Wood-46. The synthesis of DNA was activated in both B- and T-splenocytes in response to(More)
Our objective in this study was to develop and assess the diagnostic value of a coagglutination test with making use of peptidoglycane of Staphylococcus aureus in the identification of diseases of staphylococcal etiology. A total of 166 patients with diseases of staphylococcal etiology were examined. A test was elaborated of coagglutination with making use(More)
Proliferation activity of lymphocytes from rats was studied using micromethod of blast transformation reaction after exposure of X-ray irradiation (absorbed doses for animals are 0.5 and 1 Gr). The reducing of the functional activity of lymphocytes was found. There was difference in lymphocyte response induced by standard mitogens (PHA, ConA, LPS) and(More)
The data on the stimulating action of S. aureus cells, strains B-243, 2287, Wood-46, Cowan I, as well as cell-wall peptidoglycan, on the formation of endogenous colonies in the spleen of sublethally irradiated mice are presented. Teichoic acid, S. aureus ribosomal and cytoplasmic antigens produced no such effect. Whole S. aureus cells and their components(More)