V Ia Gavrilov

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The authors studied the clinical features in 19 patients with the mosaic variety of Down's disease and 63 patients with trisomia in relation to the 21st chromosome. It was demonstrated that mild forms of mental retardation are mainly seen in mosaicism rather than in the trisome variety, although severe forms of retardation may be seen in the first group as(More)
Among 330 patients with severe mental retardation who were consulted at random for medico-genetic purposes (excluding phenylketonuria and Down's disease), 27,3% constituted retarded patients due to genetic diseases, 10%--to exogenous factors. Families with a high genetical risk (25%-50% for sibs) constituted 20%. In the group of patients with severe mental(More)
The investigation of the venous blood from 62 healthy and anemic parturients and the umbilical vascular blood from their newborns has indicated that lower steroidogenic activity in the fetus was directly related to its maternal disease severity. The synthesis of dehydroepiandrosterone sulfate and the metabolism of progesterone, estrone, and estradiol are(More)
In the course of inspection 1136 persons of different age and sex data on dynamics of the main components of lipid profile, the concentration of brain-derived neurotrophic factor (BDNF) in blood plasma and indicators of levels of free cortisol, melatonin sulfate, metanephrine and normetanephrine in urine daily were obtained. Clear age and gender differences(More)
In the monitoring process 110 representatives of different age groups held a comparative analysis of the efficacy and safety of several geroprotective techniques, including the use of dry carbon dioxide baths, hyperbaric oxygen therapy, therapeutic massage and receiving Oligopeptide preparations containing complexes lysyl-glutamyl-asparagin and(More)
To assess the endocrine performance of the fetoplacental system in anemia-complicated pregnancy, blood levels of dehydroepiandrosterone sulfate (DEAS), estriol (E3), estradiol (E2), progesterone (PRG) and placental hormone were studied in 287 normal women and female patients with varying anemias. Increased levels of PRG found in the blood of anemic patients(More)
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