V. I. Sobolev

Learn More
Fungal infection is an uncommon complication after renal transplantation. We describe a rare form of mucormycosis in the renal graft. Our method was to review chart data and to perform medline searches. The patient was a 42-year-old man who underwent living-unrelated kidney transplantation in Egypt and returned to Israel on POD 8. Within the ensuing 4 weeks(More)
Psoriasis was used as a model to analyze the pathogenetic pathways of immune-mediated inflammatory diseases, and the results of bioinformatic, molecular-genetic and proteomic studies are provided. Cell mechanisms, common for the pathogenesis of psoriasis, as well as Crohn's disease, are identified. New approaches for immune-mediated diseases are discussed.
In experiments on rats, we studied the effects of experimental hyperthyroidism (subcutaneous injections of L-thyroxine, 50 μg/kg·day during 7 days) and hypercorticoidism (daily i.p. injections of hydrocortisone, 3 mg/kg·day during 30 days) on parameters of the М responses of the m. tibialis anterior after stimulation of the n. peroneus by single stimuli and(More)
Three-dimensional models of skin and epidermis imitate the structure of real tissues and provide accurate information about certain skin conditions, such as psoriasis. A three-dimensional model of mouse epidermis was generated from the epidermal keratinocytes of newborn mice and treated with cytokines. The aim of this study was to evaluate this model as an(More)
Three adrenergic responses, i. e. noradrenaline calorigenic effect, positive isoproterenol chronotropic action and seminiferous duct contraction after noradrenaline use was studied in experimental albino male rats. It was shown that hyperthyroidism provokes intensification of the beta-adrenergic responses examined (noradrenaline calorigenic effect and(More)