V I Medvedev

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Neuropeptides are shown to exert a powerful influence on mnestic processes. They actively eliminate phenomena of electric-shock amnesia, the strongest agent here being arginine vasopressin, while derivatives of oxytocin, enkephalin, and melanostatin are active to a lesser degree. The selective effect on primary learning (ACTH4-7 and Leu-enkephalin) and on(More)
A series of changes in sensory sphere take place in conditions of extremal and unusual influences. These changes are determined directly by processes at the receptor level and indirectly--by the central interaction. In spite of great variety of the influences, there are some general laws in changes of functional state of afferent systems analogous to(More)
Antiamnestic properties of memory neuropeptide--modulators and their effect on learning were studied as well as consolidation of oligopeptide ACTH4-7, vasopressin, oxytocin, leu enkephalin and the melanocyte inhibiting factor. Effect of these neuropeptides on the rat higher nervous activity is bath strong and specific: ACTH4-7 and leu enkephalin speed up(More)
The effects of vasopressin and those of fragments of adrenocorticotropin ACTH5-10; ACTH4-7; l-phenilalanin, and ACTH4-7 d-phenilalanin on the learning of rats in U-shaped labyrinth were studied. The consolidation of skills in long-term memory ability for reversal learning were checked. The results suggest that effect of all these oligopeptides on the higher(More)
The encephalographic correlations of behavioural activity of oligopeptides from the group of memory neuromodulators and similar substances (arginine-vasopressin, a fragment of adrenocorticotropine ACTH4-7 and four its analogues, leu-enkephalin and melanostatine) were studied in rabbits. The encephalogram was activated by these drugs. The fraction of(More)