V I Medvedev

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Neuropeptides are shown to exert a powerful influence on mnestic processes. They actively eliminate phenomena of electric-shock amnesia, the strongest agent here being arginine vasopressin, while derivatives of oxytocin, enkephalin, and melanostatin are active to a lesser degree. The selective effect on primary learning (ACTH4-7 and Leu-enkephalin) and on(More)
A series of changes in sensory sphere take place in conditions of extremal and unusual influences. These changes are determined directly by processes at the receptor level and indirectly--by the central interaction. In spite of great variety of the influences, there are some general laws in changes of functional state of afferent systems analogous to(More)
The delta-sleep-inducing peptide and its 10 analogues increased the total amount of slow oscillations in the rabbit EEG and shifted the spectrum towards the long-wave area. When comparing the EEGs of intact and sleep--deprived rats, the effect of delta-peptide was stronger in the latter animals. The learning of rats in U-shaped labyrinth before and after(More)
Antiamnestic properties of memory neuropeptide--modulators and their effect on learning were studied as well as consolidation of oligopeptide ACTH4-7, vasopressin, oxytocin, leu enkephalin and the melanocyte inhibiting factor. Effect of these neuropeptides on the rat higher nervous activity is bath strong and specific: ACTH4-7 and leu enkephalin speed up(More)
The encephalographic correlations of behavioural activity of oligopeptides from the group of memory neuromodulators and similar substances (arginine-vasopressin, a fragment of adrenocorticotropine ACTH4-7 and four its analogues, leu-enkephalin and melanostatine) were studied in rabbits. The encephalogram was activated by these drugs. The fraction of(More)