V. I. Goudochnikov

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Presented work is a bibliographic review about participation of glucocorticoids, cytokines and other bioregulators of stress in ontogeny of immune system and in pathogeny of infections. Besides, age-related dynamics and gender differences of morbidity and mortality caused by three infectious diseases (AIDS, pulmonary tuberculosis and sepsis) were evaluated(More)
In parallel to formulating the paradigm of developmental origins of health and disease (DOHaD), the search began on mechanisms of programming/imprinting in ontogeny. Some recent evidence has revealed the important role of glucocorticoids in such mechanisms. However, in the last decades numerous data have been accumulated on participation of other hormones(More)
The present work describes bibliographic analysis of ontogenetic changes in hormonal regulation of sleep and circadian biorhythms. It is suggested that two-stage, age-related dynamics of such changes may be related to differential occurrence registered by us earlier, of maxima of morbidity and mortality caused by a number of disorders, in middle-age and in(More)
Recently we have evaluated the role of glucocorticoids (GC) and other stress hormones in the pathogeny of age-related diseases. In order to perform this evaluation, we considered the DOHaD paradigm discussing long-term effects of adverse perinatal factors. In the present work, a part of the data collected previously was used for analyzing the role of GC in(More)
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