V G Skopichev

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A rapid growth of the uterus myoma results from the cell hypertrophy, which involves essential ultrastructural changes in the cytoplasm and the nucleus, thus suggesting the intensification cell functions. The increase in the cell volume and intensification of secretion is followed by the enlargement of the interface between the nucleus and the cytoplasm(More)
A scanning electron microscope study of the Swiss 3T3 cell surface topography was made in association with changes in proliferative activity. On the phase of logarithmic growth the cell shape is similar to that of an actively migrating fibroblast. When the growth promoting factors are depleted, the cells are seen spread and forming numerous cell-to-cell(More)
By method of scanning electron microscopy erythrocyte structure was studied in rats in carbophos poisoning. Following up to 76% acetylcholinesterase inhibition with distinct symptoms of intoxication nearly 30% of erythrocytes were deformed and tended to aggregate. Observation of blood circulation in vessels of pia mater revealed formation of erythrocyte(More)
With scanning and transmission electron microscopy characteristic changes in the endothelial lining of myometrial vessels of uterus affected with myoma were revealed. In the presence of longitudinally oriented folds and microgrowths on the luminal surface in a healthy myometrial part, a number of changes were observed in the myoma vessels. These included(More)
The culture of neurons of paravertebral sympathetic ganglia of 3--5 day old guinea pigs was obtained, fragments of the ganglia being implanted to adult rats-recipients. A migration of neuroblasts from the explant area, specific features of neurons differentiation with morphological signs appearing, and the growth of neurites forming specific growth cones,(More)
The data on distribution of cholinesterase activity in smooth myocytes of the mammary ducts and in the tissue of normal and pathologically altered myometrium are presented. In the myometrium tumorous tissue, as demonstrate hystochemical investigation results, terminals of the nervous fibers are practically absent, while in the norm they are present in the(More)
The purpose of this study was to detect the interrelationship between the increased serum concentration of the medium weight molecules (MWM) and echinocytosis, to establish the rate of echinocyte appearance in blood in endogenous and exogenous intoxications and the dependence of echinocytosis on phosphacol and carbophos doses or the degree of endogenous(More)
The light optic investigation has been performed on the 10th--15th days of lactation. The enzymatic activity has been determined by Burt method (1971). The product of histochemical reaction is revealed in the secretory cell and in the basal parts of the alveoli, that corresponds to location of myoepithelial cells. Localization of the reaction product in the(More)
Cholinesterase (ChE) localization in the alveolar compartment of the mammary gland has been studied by light microscopy and ultrahistochemical methods. The product of reaction to ChE is associated with micropinocytotic vesicles of the capillar endothelium and myoepithelial cells, separate nerve terminals in interalveolar connective tissue and perivascular(More)