V F Strel'tsov

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In rats rearing in social isolation since 17th day of life and treated with 5-15% ethanol solution within 3 months, the effects of antidepressants on self-stimulation of lateral hypothalamus and place preference were studied. The comparative study of seven antidepressants with different mechanism of action (fluoxetine, maprotiline, tianaptine, pyrazidol,(More)
The behavioral effects of native human corticotropin-releasing hormone (CRH) and its agonists D-Glu-20 (R1) and D-Pro-5 (R2) introduced (0.01 - 1 microg) into the lateral brain ventriculi of Sprague-Dowley rats have been studied in the open field, dark - light, Y-maze, and place preference tests. The different effects of CRH and its agonists on the anxiety(More)
Amphetamine (1 mg/kg), morphine (1 mg/kg), and ethaminal sodium (5 mg/kg) activated self-stimulation reaction of lateral hypothalamus in rats. In contrast, intraamygdalary injections of astressin (1 microg/microl), which is a nonselective antagonist of corticoliberin receptors, inhibited this reaction. The astressin blockade of extrahypothalamic(More)
6-Hydroxydopamine, which induces selective degeneration of the dopaminergic system of the brain, was given intraamniotically to rats on days 13 and 17 of intrauterine development at a dose of 75 microg/fetus. Similar experiments were performed with 6-hydroxydopamine on days 4 and 10 of neonatal life. Rats were subsequently reared and motor and emotional(More)
6-Hydroxydopamine (75 mkg), producing selective degeneration of dopaminergic neurons in the brain, was injected intraamniotically to every rat fetus on 13th or 17th day of mother pregnancy. The other experiment was performed, when 6-hydroxydopamine administered i.p. to newborn rats on 4th or 10th day of life. All rats were growing, and several(More)
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