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This prospective, Post-Authorization Safety Surveillance (PASS) study was carried out in patients with hemophilia A or B and inhibitors treated with FEIBA for 1 year to collect real-world data on safety and effectiveness of FEIBA. The study followed a cohort design and did not make stipulations on treatment or observation schedule, as it was designed to(More)
BACKGROUND Developing inhibitors is a rare event during the treatment of hemophilia A. The multifacets and uncertainty surrounding the development of inhibitors further complicate the process of estimating inhibitor rate from the limited data. Bayesian statistical modeling provides a useful tool in generating, enhancing, and exploring the evidence through(More)
In sphere of research of discrete optimization algorithms efficiency the important place occupies a method of polynomial reducibility of some problems to others with use of special purpose components. In this paper a novel method of compact representation for sets of binary sequences in the form of " compact triplets structures " (CTS) and " compact couples(More)
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