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Several functions were used to model the fixed part of the lactation curve and genetic parameters of milk test-day records to estimate using French Holstein data. Parametric curves (Legendre polynomials, Ali-Schaeffer curve, Wilmink curve), fixed classes curves (5-d classes), and regression splines were tested. The latter were appealing because they(More)
Transposon mutagenesis of Mycobacterium smegmatis mc2155 enabled the isolation of a mutant strain (called LGM1) altered in the regulation of piperidine and pyrrolidine utilization. The complete nucleotide sequence of the gene inactivated in mutant LGM1 was determined from the wild-type strain. This gene (pipR) encoded a member of the GntR family of(More)
In proportional hazards models, the hazard of an animal A(t), ie, its probability of dying or being culled at time t given it is alive prior to t, is described as A(t) = '>" o (t)e W ' e where A o (t) is a 'baseline' hazard function and e w 'B represents the effect of covariates w on culling rate. A distribution can be attached to elements sq in 0,(More)
The objectives of this study were to estimate the heritabilities for and genetic correlations among resistance to bacterial cold-water disease and growth traits in a population of rainbow trout (Oncorhynchus mykiss). Bacterial cold-water disease, a chronic disease of rainbow trout, is caused by Flavobacterium psychrophilum. This bacterium also causes acute(More)
The purposes of this study were 1) to investigate the heritability, reliability, and selection response for survival traits following a Weibull frailty proportional hazard model; and 2) to examine the relationship between genetic parameters from a Weibull model, a discrete proportional hazard model, and a binary data analysis using a linear model. Both(More)
Size of the reference population and reliability of phenotypes are crucial factors influencing the reliability of genomic predictions. It is therefore useful to combine closely related populations. Increased accuracies of genomic predictions depend on the number of individuals added to the reference population, the reliability of their phenotypes, and the(More)
This study demonstrated five different approaches, with and without time-dependent covariates, to determine the effect of disease on culling. It was also of interest to determine whether the time of the disease had an effect on subsequent culling (i.e., whether disease should be treated as time-dependent covariate). To this purpose, five separate models(More)
The relationship between mastitis and functional longevity was assessed with survival analysis on data of Danish Black and White dairy cows. Different methods of including the effect of mastitis treatment on the culling decision by a farmer in the model were compared. The model in which mastitis treatment was assumed to have an effect on functional(More)
Genetic parameters related to growth, carcass composition and egg production were estimated on three (two female and one male) commercial strains of turkey using the method of restricted maximum likelihood (R.EML). In order to account for the sexual dimorphism in turkeys, body weight (BW, measured at 12 and 16 weeks of age) was considered as a sex-limited(More)
Genetic parameters of 7 traits measured in central test stations-average daily gain (ADG1), feed conversion ratio (FCR) and backfat thickness (ABT) measured on candidates for selection, and average daily gain (ADG2), dressing percentage (DP), estimated carcass lean content (ECLC) and meat quality index (MQI) measured in slaughtered relatives-were estimated(More)