V. C. Pandey

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Cerebral microvessels from rats were prepared and characterized by their enrichment of specific markers, namely alkaline phosphatase (AP) and tau-glutamyl transpeptidase (tau-GT). Further, it was observed that AP and tau-GT registered marked increase in aged rats. On the contrary, lactate dehydrogenase (LDH) activity decreased with the increasing age.(More)
BACKGROUND p53 is the most studied tumor suppressor and its overexpression may or may not cause cell death depending upon the genetic background of the cells. p53 is degraded by human papillomavirus (HPV) E6 protein in cervical carcinoma. Several stress activated kinases are known to phosphorylate p53 and, among them cyclin dependent kinase 5 (Cdk5) is one(More)
The aim of present study was to explore and document medicinal plants used for the traditional dermatological healthcare management practices by the the Tharu tribal community of Uttar Pradesh. The study was conducted during 2000–2004. Information was gathered from 230 informants residing in 46 villages in Terai region of Indo-Nepal boarder using(More)
The aim of the present investigation was to document the phytotherapeutic knowledge and veterinary healthcare management practices among the Tharu tribal community of Uttar Pradesh, India and to determine the consensus of such practices, in order to evaluate the potential for new veterinary drugs of herbal origin. This study was conducted in 2000–2004 using(More)
Leucaena leucocephala (Lam.) de Wit. is native to Central America and Mexico, but now grows naturally in most tropical areas globally. It is a neglected and underutilized; medium to small sized tree of multiple values. It is commonly known as wild tamarind in English and subabul in Hindi. In recent years, Leucaena has gained a great attention for its(More)
Elevated glycemic index, an important feature of diabetes is implicated in an increased risk of hepatocellular carcinoma (HCC). However, the underlying molecular mechanisms of this association are relatively less explored. Present study investigates the effect of hyperglycemia over HCC proliferation. We observed that high glucose culture condition (HG)(More)
Plasmodium yoelii infected cerebral microvessels of mice had an enhanced time-dependent, temperature-sensitive, and saturable uptake of [14C]-amino acid. viz. leucine, valine and glycine. Metabolic inhibitors caused a noticeable inhibition of amino acid uptake in normal microvessels as compared to infected cerebral microvessels indicating that the uptake of(More)
Saccharum spontaneum L. is a perennial tall grass and invades naturally abandoned and pastoral lands in many tropical countries. Although it is a potentially multiple-use and multifunctional species, it remains neglected and underutilized. It is commonly known as ‘Wild cane’ in English and ‘Kans’ in Hindi. In recent years, S. spontaneum has attracted(More)
BACKGROUND Obesity-related cellular, metabolic, and molecular alterations have been shown to increase cancer risk and tumor progression and are associated with poorer therapeutic outcome in cancer patients. However, the impact of obesity and weight-control interventions on the therapeutic response in melanoma is poorly understood. METHODS High fat diet(More)
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