V. Aparna

C. Sadasivan1
K. V. Dileep1
1C. Sadasivan
1K. V. Dileep
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Primary oral mucosal melanoma is a rare aggressive neoplasm and accounts for only 0.2-8% of all reported melanomas. It is a malignant neoplasm of melanocytes that may arise from a benign melanocytic lesion or de novo from melanocytes within normal skin or mucosa. It is considered to be the most deadly and biologically unpredictable of all human neoplasms,(More)
Docking and pharmacophore screening tools were used to examine the binding of ligands in the active site of thymidine monophosphate kinase of Mycobacterium tuberculosis. Docking analysis of deoxythymidine monophosphate (dTMP) analogues suggests the role of hydrogen bonding and other weak interactions in enzyme selectivity. Water-mediated hydrogen-bond(More)
Fatty acids have gained therapeutic attention because of their nutritional and health implications. The potentialities of different fatty acids as PLA2 binders have been analysed using molecular docking studies. Among the 46 fatty acids selected for docking studies, erucic acid and linoleic acid gave the highest glide scores. The earlier reported palmitic(More)
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