V. A. Sashkov

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Model experiments were performed to study the gender-related characteristics of the dynamics of sex steroids in the brain during the acquisition and extinction of a conditioned reflex. Before acquisition of conditioned reflexes, females had greater anxiety and fear than males. On formation of the conditioned reflex, there were no significant gender-related(More)
Sexual peculiarities of dynamics of brain sex steroids in the process of learning and extinction of the conditioned reflex of passive avoidance have been studied in model experiment. Prior to learning of conditioned reflex, females were found to be distinguished by manifestation of anxiety and fear as compared with males. At formation of the conditioned(More)
Relationship between the blood level of calcium and the level of catecholamines in the brain limbic structures was studied in passive avoidance conditioning and extinction in rats with hypoparathyreosis. After parathyroidectomy, conditioning processes were shown to be impaired as a result of a disorder of calcium supply. In hypoparathyreosis, not only the(More)
Interactions between the total blood calcium level and catecholamine contents in limbic brain structures during the formation and extinction of a conditioned passive avoidance reflex were studied in rats with hypoparathyroidism. Impairments of calcium support for the processes of conditioned reflex activity were seen after removal of the parathyroid glands.(More)
We investigated gender-related differences in dynamics of the brain sexual steroids during learning and the decrease of conditioned reflex in the modeling experiment. It was revealed that, before training to conditioned reflexes, females manifested a greater anxiety than males. Significant differences between males and females in formation of the(More)
We studied the level of neuroactive steroids in the brain, behavior in the “open field,” and the anxiety and phobia status in maturing and mature female rats during the estrous cycle. In female rats aged 2 and 6 months, we found rhythmic changes in the content of corticosterone, testosterone, and estradiol in hypothalamus, hippocampus, amygdala, cingulated(More)
Changes in the brain’s neuroactive steroid levels, behavior in the open field, and the anxious-phobic status of male and female rats in the course of development have been studied. An increase in the motor and exploratory activity and emotionality in rats of both sexes in the pubertal period and a decrease in their values in mature and old animals have been(More)
Sex-related peculiarities of dynamics of brain sex steroids in the process of learning and extinction of the conditioned reflex of passive avoidance have been studied in model experiment. Prior to learning of the conditioned reflex, female rats were found to be distinguished by manifestation of anxiety and fear as compared with male rats. At formation of(More)
We investigated the levels of neuroactive steroids, behavior, and anxiety in the brains of male rats with different hormonal status. We revealed a correlation between motor and exploratory activities, emotionality, and anxiety and the concentrations of corticosterone, testosterone, and estradiol in the hypothalamus, hippocampus, amygdala, cingulated gyrus,(More)
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