V. A. Paseshnichenko

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Data concerning the discovery of an alternative non-mevalonate pathway for isoprenoid biosynthesis leading to isopentenyl diphosphate formation are reviewed. This pathway has been discovered in experiments with several eubacteria producing triterpenoids of the hopane series. 13C-labeled acetate, glucose, and triose phosphates were used as precursors. The(More)
From the rhizome D. deltoidea a new trisaccharide of diosgenine has been isolated. This compound is diosgenine-3 (alpha-L-rhamnopyranosyl (1-->2gl)-beta-D-glucopyranosyl-(1-->4 gl)-beta-D-glucopyranoside. This trisaccharide has been termed deltonine. The rhizome D. deltoidea has also displayed furostanolic tetrasaccharide which is a mixture of(More)
The natural agent deltostim is a mixture of furanostanol steroid glycosides characterized by a high anabolic and a low androgenic activities. In doses of 5–30 mg/kg it stimulates the production of proteins and nucleic acids in the skeletal and cardiac muscles. These doses do not suppress biopolymer production in the liver, which indicates that the agent is(More)
Parasitic nematodes are considered as a biogenic stress factor in plants. The effects of various plant isoprenoids, including mono-, sesqui-, di-, and triterpenoids, sterols, and steroid glycosides, on parasitic nematodes are reviewed. Certain isoprenoids can be placed in the class of natural plant adaptogens.
The adaptogenic effect of furostanol glycosides of Dioscorea deltoidea Wall on plants was first observed by us in tomatoes and cucumbers infected with the gall nematode. Phytonematodes cause stress in plants, which leads to significant disturbances in homeostasis in the cell, related to changes in the structure of biological membranes. Furostanol glycosides(More)