V. A. Levitskii

  • Citations Per Year
Learn More
Pathomorphological examination of large bronchi in patients with occupational diseases, lung cancer, and in subjects exposed to radiation revealed structural and functional heterogeneity of the epithelium: the presence of focal atrophy, metaplasia, hyper- and dysplasia in the same biopsy specimen. This phenomenon was termed as instability of the epithelium.(More)
Operations were conducted on 21 patients for bronchial asthma. Four of them suffered from the hormone-dependent form of the disease. The duration of the disease ranged from 12 months to 18 years. The operations were performed under local anesthesia through a left approach. The internal branch of the superior laryngeal nerve was exposed and identified and a(More)
Imidazoquinolins represent a new group of compounds that recently entered into clinical practice as anti-tumor and anti-viral immune modulators. They are low molecular weight synthetic guanosine-like molecules. Although imiquimod, the most widely used imidazoquinolin, is recommended for the treatment of several forms of skin cancer and papillomas, the(More)
Biopsy specimens from large bronchi of patients with central and peripheral pulmonary cancer were studied. Central cancer was associated with hyperplasia and dysplasia of the epithelium, hyperplasia of glandular compartment, and pronounced immunocompetent cell response. Peripheral cancer was characterized by predominance of atrophic and sclerotic changes,(More)
Diffuse progressive atrophy of the bronchial epithelium and mucosa are the main changes detected in the biopsy specimens of large bronchi in lung cancer. Unstability of the bronchial epithelium in lung tumors (alternating atrophy, metaplasia, hyperplasia, and dysplasia) is described.
Monoclonal antibodies (McAb) to human IgM, capable of recognizing antigenic determinants of different character, have been obtained. Three type-specific McAb have been used in diagnostic systems for the determination of specific IgM antibodies in the sera of patients with hepatitides A and B. The affinity constant and high specificity of McAb have made it(More)