V. A. Kamysheva

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In experiments on rats forced to swim while carrying a load, sodium hydroxybutyrate was found to have a normalizing effect on the ammonia content in the striated muscles, a biochemical indicator of physical fatigue. Whereas in control rats not receiving hydroxybutyrate swimming led to a marked (more than twofold) increase in the ammonia content in muscle(More)
Enkephalins inhibit activity of the negative reinforcement system by their action on its perceptual and emotional components [i]. The inhibiting effect of LE is stronger than that of ME, evidently due to its stimulating action on the "reward" system, which reciprocally depresses the activity of the negative reinforcement system [2]. Information in the(More)
tive reinforcement systems and the antinociceptive systems of the brain [4]. It has now been shown that the antinocieeptive effect is not only a mechanism of central analgesia, but also an operant method of self-regulation and self-protection from the effects of s t ress , and it is realized both by a decrease in the intensity of the ascending nociceptive(More)
Adaptogenic effect of mebikar was revealed in experiments on cats, mice and rats. The drug was shown to decrease the emotional stress and to completely remove the stupor-like state in cats induced by stress situation and pain stimulation. The drug slightly increased the lifespan of animals under hypoxic hypoxia and raised the limits of maximum tolerable(More)
The experiments on rats exposed to compulsory swimming have shown the normalizing effect of sodium hydroxybutyrate with respect to one of the biochemical indices of physical overwork: the ammonia level in cross-striated muscles. In control rats who had not received the drug, the swimming induced a significant (more than twofold) increase in the muscle(More)
It has been shown that anticholinergic receptor (ACR) antibodies, obtained by immunization of rabbits with cholinergic receptors isolated from motor-denervated skeletal muscles of Balb/c mice, were able to block the cholinergic receptors of mouse splenic lymphocytes by preventing the action of cholinergic drugs on them [1, 2]. This blockade indirectly(More)