Vítor Filipe

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In experimental peripheral nerve studies, the rat sciatic nerve model is widely used to examine functional changes after different surgical repairs or pharmacological treatments, following nerve injury. The number and diversity of tests which have been used to assess functional recovery after experimental interventions often makes it difficult to recommend(More)
Computerized analysis of rat gait is becoming an invaluable technique used by some peripheral nerve investigators for the evaluation of function. In this article we describe the use of a biomechanical model of the foot and ankle that allows a quantitative assessment and description of the ankle angle, reflecting plantarflexion and dorsiflexion during the(More)
This paper presents a system which extends the use of the traditional white cane by the blind for navigation purposes in indoor environments. Depth data of the scene in front of the user is acquired using the Microsoft Kinect sensor which is then mapped into a pattern representation. Using neural networks, the proposed system uses this information to(More)
Peripheral nerve researchers frequently use the rat sciatic nerve crush model in order to test different therapeutic approaches. The purpose of this study was to determine the sequence of changes after an axonotmetic injury by means of a biomechanical model of the foot and ankle, and compare them with walking track analysis, over a fixed period of time. A(More)
The influence of reduced feedback from the cutaneous receptors in the hindpaw in rat locomotion is still unclear. To evaluate this question, we conducted a detailed hindlimb kinematic analysis in animals, which suffered complete loss of thermal sensation. Two-dimensional hindlimb kinematics, temporal and spatial measurements, and walking track analysis were(More)
Numerous animal model studies in the past decade have demonstrated that pharmacological elevation of cyclic AMP (cAMP) alone, or in combination with other treatments, can promote axonal regeneration after spinal cord injury. Elevation of cAMP via the phosphodiesterase 4 (PDE4) inhibitor, rolipram, decreases neuronal sensitivity to myelin inhibitors,(More)
In experimental peripheral nerve studies, the rat sciatic nerve model is widely used to examine functional outcome following nerve injury and repair. A variety of evaluation methods exist in the literature, but an adequate selection continues to be a critical point for the researcher. Rats with sciatic nerve injury typically ambulate with an external(More)
The convenience of the motor-driven treadmill makes it an attractive instrument for investigating rat locomotion. However, no data are available to indicate whether hindlimb treadmill kinematic findings may be compared or generalized to overground locomotion. In this investigation, we compared overground and treadmill locomotion for differences in the(More)
Visual impairment and blindness caused by infectious diseases has been greatly reduced, but increasing numbers of people are at risk of age-related visual impairment. Visual information is the basis for most navigational tasks, so visually impaired individuals are at disadvantage because appropriate information about the surrounding environment is not(More)
Radio frequency identification (RFID) is one of the automatic identification technologies more in vogue nowadays. There is a wide research and development in this area trying to take maximum advantage of this technology, and in coming years many new applications and research areas will continue to appear. This sudden interest in RFID also brings about some(More)