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Interaction of Saccharomyces boulardii with Salmonella enterica Serovar Typhimurium Protects Mice and Modifies T84 Cell Response to the Infection
Background Salmonella pathogenesis engages host cells in two-way biochemical interactions: phagocytosis of bacteria by recruitment of cellular small GTP-binding proteins induced by the bacteria, andExpand
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Saccharomyces boulardii inhibits inflammatory bowel disease by trapping T cells in mesenteric lymph nodes.
BACKGROUND & AIMS Saccharomyces boulardii is a nonpathogenic yeast used for treatment of diarrhea. We used a mice model of inflammatory bowel disease (IBD) to analyze the effects of S boulardii onExpand
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Structure–function insights reveal the human ribosome as a cancer target for antibiotics
Many antibiotics in clinical use target the bacterial ribosome by interfering with the protein synthesis machinery. However, targeting the human ribosome in the case of protein synthesisExpand
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Increased CD271 expression by the NF-kB pathway promotes melanoma cell survival and drives acquired resistance to BRAF inhibitor vemurafenib
Specific BRAFV600E inhibitors (BRAFi) are highly effective in the treatment of melanoma. However, acquired drug resistances invariably develop after the initial response. Therefore, theExpand
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Saccharomyces boulardii Modifies Salmonella Typhimurium Traffic and Host Immune Responses along the Intestinal Tract
Salmonella enterica serovar Typhimurium (ST) is an enteropathogenic Gram-negative bacterium that causes infection following oral ingestion. ST spreads rapidly along the gastrointestinal tract (GIT)Expand
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P.305 Effet anti-inflammatoire de Saccharomyces boulardii via l’inhibition de NF-κB sur un modèle murin de colite au TNBS : exemple d’une application en imagerie
Introduction Dans l’arsenal therapeutique visant a traiter la maladie de Crohn, sont apparues des molecules anti-inflammatoires dont la cible pharmacologique est le facteur de transcription NF-κB.Expand
O59 La GTPase Rab4b des lymphocytes T participe à l’homéostasie glucolipidique chez la souris
Introduction L’expression de la GTPase Rab4b est diminuee dans le tissu adipeux (TA) de souris et de patients obeses. Rab4b est principalement exprime dans les cellules immunitaires dont lesExpand
P.313 - Effet de Saccharomyces boulardii lors d’infections par Salmonella enterica serovar Typhimurium
Introduction Le pouvoir pathogene de Salmonella est lie a son pouvoir invasif et a la reponse inflammatoire de la cellule infectee. L’activation de la voie Rac est impliquee dans l’invasion de laExpand