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  • Laurie Scott, Chantra Eskes, +26 authors Valérie Zuang
  • Biology, Medicine
  • Toxicology in vitro : an international journal…
  • 2010 (First Publication: 1 February 2010)
  • In spite of over 20 years of effort, no single in vitro assay has been developed and validated as a full regulatory replacement for the Draize Eye Irritation test. However, companies have been usingContinue Reading
  • H. Spielmann, Michael Balls, +16 authors P. G. Brantom
  • Biology, Medicine
  • Toxicology in vitro : an international journal…
  • 1998 (First Publication: 1 June 1998)
  • To date, no standardized international guideline for the testing of chemicals for phototoxic potential has been accepted for regulatory purposes. In 1991, the European Commission (EC), representedContinue Reading
  • Nathalie Alépée, Sandrine Bessou‐Touya, +10 authors Pauline M. McNamee
  • Biology, Medicine
  • Toxicology in vitro : an international journal…
  • 2013 (First Publication: 1 August 2013)
  • Cosmetics Europe, The Personal Care Association, known as Colipa before 2012, conducted a program of technology transfer and assessment of Within/Between Laboratory (WLV/BLV) reproducibility of theContinue Reading
  • P. G. Brantom, Leon H. Bruner, +39 authors Mark Stern
  • Biology, Medicine
  • Toxicology in vitro : an international journal…
  • 1997 (First Publication: 1 February 1997)
  • The principal goal of this study was to determine whether the results from a set of selected currently available alternative methods as used by cosmetics companies are valid for predicting the eyeContinue Reading
  • Els Adriaens, João Barroso, +9 authors Valérie Zuang
  • Medicine, Chemistry
  • Archives of Toxicology
  • 2013 (First Publication: 1 March 2014)
  • For more than two decades, scientists have been trying to replace the regulatory in vivo Draize eye test by in vitro methods, but so far only partial replacement has been achieved. In order to betterContinue Reading
  • Warren John Pape, Tobias Maurer, Uwe Pfannenbecker, Winfried Steiling
  • Biology, Medicine
  • Alternatives to laboratory animals : ATLA
  • 2001 (First Publication: 1 March 2001)
  • In the EU/COLIPA validation programme on “Photoirritation in vitro”, two core tests and a number of mechanistically based tests were carried out to examine their suitability as regulatory tests forContinue Reading
  • Warren John Pape, Martin Brandt, Uwe Pfannenbecker
  • Chemistry, Medicine
  • Toxicology in vitro : an international journal…
  • 1994 (First Publication: 1 August 1994)
  • 12 well-known phototoxicants used in the EC/COLIPA (The European Cosmetic, Toiletry and Perfumery Association) interlaboratory validation trial on 'Photoirritation in vitro' have been analysed inContinue Reading