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  • Uwe Nordemann, David Wifling, +4 authors Armin Buschauer
  • Medicine, Biology
  • PloS one
  • 2013 (First Publication: 2 September 2013)
  • The investigation of the (patho)physiological role of the histamine H4 receptor (H4R) and its validation as a possible drug target in translational animal models are compromised by distinctExpand
  • David Wifling, Karoline Loeffel, +5 authors Armin Buschauer
  • Medicine, Chemistry
  • British journal of pharmacology
  • 2015 (First Publication: 1 February 2015)
  • BACKGROUND AND PURPOSE Some histamine H4 receptor ligands act as inverse agonists at the human H4 receptor (hH4 R), a receptor with exceptionally high constitutive activity, but as neutralExpand
  • Roland Geyer, Uwe Nordemann, Andrea Straßer, Hans-Joachim Wittmann, Armin Buschauer
  • Medicine, Chemistry
  • Journal of medicinal chemistry
  • 2016 (First Publication: 5 April 2016)
  • 2-Cyano-1-[4-(1H-imidazol-4-yl)butyl]-3-[2-(phenylsulfanyl)ethyl]guanidine (UR-PI376, 1) is a potent and selective agonist of the human histamine H4 receptor (hH4R). To gain information on the activeExpand