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BACKGROUND A number of studies have reported evidence of cognitive deficits in euthymic bipolar patients. Qualitative reviews of the literature have indicated impairments in executive functions and declarative memory are most consistently reported. However, not all primary studies conducted to date have had sufficient power to detect statistically… (More)
BACKGROUND Neurocognitive deficits exist in euthymic patients with bipolar disorder, but relationships between symptoms, psychosocial and neurological factors remain uncertain. AIMS To measure neurocognitive function in bipolar disorder and explore links to sub-syndromal mood symptoms, soft neurological signs and psychosocial impairment. METHOD… (More)
BACKGROUND ECT, though not favoured in the West for treating schizophrenia, is regularly practiced in India for this indication, particularly in poorly responding/treatment resistant cases.Therefore, its role in treatment-resistant schizophrenia is a subject of systematic investigation. AIM To compare the effectiveness and safety of Electroconvulsive… (More)
OBJECTIVES To assess the prevalence and the spectrum of psychosocial morbidity and its correlation with various social and disease-related factors in children with beta thalassemia major. STUDY DESIGN Sixty children with transfusion-dependent beta thalassemia major were included in the study group who fulfilled these inclusion criteria: 1) age 5 to 15… (More)
A psychiatric survey was carried out in an urban area of Ahmedabad which consisted mainly of middle class population. 461 families were surveyed which consisted of a total number of 2712 persons.The data was collected in a predetermined form. The index cases were individually evaluated in detail with the help of a structured Psychiatric proforma, case work… (More)
Two atypical cases of rabies, mimicking respectively schizophrenic psychosis and acute manic excitement, are reported along with autopsy data. The importance to recognize these variants, particularly in rabies prevalent areas, is emphasized. The potential sources of diagnostic confusion are discussed, along with a review of the relevant literature.
Two cases are reported in which simple writer's cramp turned into dystonic writer's cramp without progression to generalized dystonia. Such a transition casts doubt on the conventional nosological status of writer's cramp as a functional motor disorder related to occupation; it suggests that the condition may be minor manifestation of focal dystonia.
BACKGROUND Soft neurological signs (SNS) are found to be in excess in bipolar disorder (BD). This paper explores changes in SNS with ageing to ascertain whether BD is associated with a progressive neurological decline or a relatively fixed, persistent deficit. METHODS 53 euthymic BD subjects and controls, aged 15-55 years, were for examined for the… (More)
Recently, the Drugs Controller General of India (DCGI) has written to several organizations seeking information on their infrastructure for drug trials. The DCGI was actually trying to figure out the Good Clinical Practice (GCP) training requirements at the national level. The DCGI wishes to build up a pool of GCP trained clinicians in the country by… (More)
Restraint and seclusion has been used to manage patients despite all controversies. Our study analyzed the opinions of different psychiatrists on the use of this method in their clinical practice. Most of them (80%) practice restraints as a treatment modality and believe that they are integral to the management of psychiatric patients. None is using… (More)