Utku Kürșat Ercan

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Oxidative stress leads to membrane lipid peroxidation, which yields products causing variable degrees of detrimental oxidative modifications in cells. Reactive oxygen species (ROS) are the key regulators in this process and induce lipid peroxidation in Escherichia coli. Application of nonthermal (cold) plasma is increasingly used for inactivation of surface(More)
Topical delivery of nitric oxide (NO) through a wound dressing has the potential to reduce wound infections and improve healing of acute and chronic wounds. This study characterized the antibacterial efficacy of an ointment containing NO-loaded, zinc-exchanged zeolite A that releases NO upon contact with water. The release rate of NO from the ointment was(More)
By applying dielectric-barrier discharge nonthermal plasma technique, we have treated fluids and generated antimicrobial solutions, tested for properties such as changes in pH, temperature, delay time, holding time, fluid-aging, and detection and comparison of acid and hydrogen peroxide. All plasma-treated solutions showed strong biocidal activity, and(More)
In continuation of our previous reports on the broad-spectrum antimicrobial activity of atmospheric non-thermal dielectric barrier discharge (DBD) plasma treated N-Acetylcysteine (NAC) solution against planktonic and biofilm forms of different multidrug resistant microorganisms, we present here the chemical changes that mediate inactivation of Escherichia(More)
PURPOSE To evaluate the effect of different surface treatments and bonding procedures on the tensile bond strength (TBS) of resin composites repaired 6 months after polymerization. MATERIALS AND METHODS Resin composite sticks were aged in distilled water at 37°C for 6 months. They were divided into 12 groups (n = 10) according to the combination of(More)
Infection and inflammation are common complications that seriously affect the functionality and longevity of implanted medical implants. Systemic administration of antibiotics and anti-inflammatory drugs often cannot achieve sufficient local concentration to be effective, and elicits serious side effects. Local delivery of therapeutics from drug-eluting(More)
The aim of this study was to investigate the synergistic effect of cold atmospheric plasma (CAP) treatment and RGD peptide coating for enhancing cellular attachment and proliferation over titanium (Ti) surfaces. The surface structure of CAP-treated and RGD peptide-coated Ti discs were characterized by contact angle goniometer and atomic force microscopy.(More)
Many injectables are not amenable to standard sterilization methods, which destroy sensitive materials. This is particularly true for ultrasound contrast agents (UCA) consisting of gas bubbles stabilized by a surfactant or polymer shell. We investigated a new method to achieve safe and effective sterilization in production by introducing dielectric-barrier(More)
Several studies compared two dielectric barrier discharge (DBD) plasma treatment regimes and their effect on viable bacteria inactivation e.g. [1, 2]. Significant difference was shown between direct and indirect treatments where plasma either contacts the surface being treated or does not. The sterilization efficiency drops by almost an order of magnitude(More)
Published Ahead of Print 3 January 2011. 10.1128/AAC.01002-10. 2011, 55(3):1053. DOI: Antimicrob. Agents Chemother. Alexander Fridman and Ari D. Brooks Paff, Utku K. Ercan, Gregory Fridman, Gary Friedman, Suresh G. Joshi, Moogega Cooper, Adam Yost, Michelle Escherichia coli Lipid Peroxidation in Oxidative DNA Damage and Membrane Plasma-Induced Inactivation(More)