Urban J. Lindgren

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The Neck Disability Index was tested for validity and reliability. Fifty-nine Swedish patients (28 men, 31 women) were included. Twenty patients were in the acute phase after a neck sprain, 19 had chronic neck pain and 20 had no neck pain but had other musculoskeletal symptoms. On 5 occasions, the patients completed the Neck Disability Index, the Disability(More)
A prospective, randomized study comparing the compression hip screw with the Gamma nail in the treatment of 426 intertrochanteric fractures is reported. The median patient age was 80 years, and 71% were women The compression hip screw operation took less time except in Evans Type 5 fractures. Blood loss generally was less in the compression hip screw group(More)
Mesenchymal stem cells (MSC) can differentiate into osteoblasts, adipocytes, chondrocytes and myoblasts. It has been suggested that a reciprocal relationship exists between the differentiation of MSC into osteoblasts and adipocytes. Peroxisome proliferator-activated receptor gamma2 (PPARgamma2) is a key element for the differentiation into adipocytes.(More)
The effect of ovarian insufficiency on calcium metabolism has been thought to involve an increased bone resorptive effect of parathyroid hormone and possible impaired synthesis of 1,25-dihydroxyvitamin D3. In the present study a rat model allowing for controlled serum levels of parathyroid hormone and 1,25-dihydroxyvitamin D3 was used. Oophorectomy in this(More)
The risk of fracturing the proximal femur is high for individuals with metabolic bone disease or with low bone mass associated with advanced age. Incidences of 20,538 trochanteric and femoral neck fractures in adult Swedish men and women, from a computerized medical information register for all hospitals in Stockholm County, were analyzed for age- and(More)
We studied the incidence of cervical and trochanteric hip fractures in Stockholm, Sweden from 1972 through 1981. The material, selected from a computerized medical information register, consisted of 11 812 cervical fractures and 8094 trochanteric fractures. The incidence did not change in the age group 50-74 years. In males 75 years of age and older, the(More)
A distal oblique osteotomy on the first metatarsal, with lateral displacement of the metatarsophalangeal joint and internal fixation with a compression screw, was performed. No splint or plaster was used. The operation is relatively simple and effective. Pain and discomfort during a short healing period are minimal. Forty-nine feet were operated on in 42(More)
BACKGROUND Less invasive approaches for hip arthroplasty have been developed in order to decrease traumatisation of soft tissue and shorten hospital stay. However, the benefits with a new technique can be at the expense of a new panorama of problems. This manuscript describes, with emphasis on postoperative complications, our experience from the first 200(More)
Periarticular heterotopic bone (HB) formation after hip arthroplasty can be prevented by indomethacin or radiation. It is therefore important to identify patients at risk. The authors analyzed 124 consecutive cases of primary total hip arthroplasty (THA) performed by the same trans-trochanteric operative approach in 124 patients. Heterotopic bone occurred(More)
Human aging is associated with a progressive decline in bone mass and an accumulation of marrow fat. We found that osteoblast differentiation was reduced and adipocyte formation increased in bone marrow stromal cells derived from aged mice compared with young controls. The increased adipogenesis correlated with a relatively lower Sirt1 activity and a lower(More)