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One of the goals of early treatment of Class III malocclusion with maxillary expansion and protraction headgear is to significantly improve the dentofacial profile. The objectives of the present study were to determine (1) the interrelationships of the soft tissue and dentoskeletal profiles after maxillary expansion and protraction headgear treatment and(More)
A prospective clinical trial was conducted to determine the skeletal and dental contributions to the correction of overjet and overbite in Class III patients. Thirty patients (12 males and 18 females with a mean age of 8.4 +/- 1.7 years) were treated consecutively with protraction headgear and fixed maxillary expansion appliances. For each patient, a(More)
Factors regulating condylar growth have not been identified before. This study was designed to identify a series of these factors, such as Sox 9 transcription factor and vascular endothelial growth factor (VEGF), and also to correlate the amount of type X collagen expressed during natural growth to the amount of bone newly formed. We used 115 Sprague-Dawley(More)
A prospective clinical trial was conducted to determine the cephalometric and occlusal changes following maxillary expansion and protraction. Twenty Southern Chinese patients (eight males and 12 females with a mean age of 8.4 +/- 1.8 years) with skeletal Class III malocclusions were treated consecutively with maxillary expansion and a protraction facemask.(More)
We have previously shown distinct effects of shear stress and pressure on transcription of several potent vascular mediators. In the present study, we tested the hypothesis that c-jun and c-fos are regulated differentially by shear and pressure. Intact human umbilical veins were perfused with various combinations of shear and pressure during 1.5, 3 and 6 h.(More)
The accuracy and precision of a method devised for estimation of chronological age based on tooth formation (Demirjian et al 1973) using its latest standards (Demirjian 1982, 1986) were investigated using 204 panelipses obtained from a randomised sample of 5-7 year old Chinese children. The precision was found to be high but the accuracy was low. The mean(More)
The aim of the present study was to investigate the temporal pattern of expression of VEGF (Vascular Endothelial Growth Factor) and new bone formation in the condyle during forward mandibular positioning. The importance of vascularization during endochondral ossification was investigated during natural growth of the condyle and compared to that after(More)
Longitudinal data on adolescent growth in height and skeletal development of the hand and wrist were collected as part of a prospective study of the growth and development of 212 randomly selected Swedish urban children. The onset, peak and end of the pubertal growth spurt were defined on the unsmoothed incremental curve of height. The skeletal development(More)
The study was designed to investigate the accuracy and precision of the development of the third mandibular molar, determined on panoramic x-rays, as an indicator of chronological age- a method which is used in Sweden to estimate chronological age in certain young foreign individuals with uncertain birth records. Accuracy test: The mean difference between(More)