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BACKGROUND The increasing use of antimicrobiaL drugs is resulting in enormous hospital expenditures. Careful assessment of inappropriate prescribing and a search for more cost-effective treatment strategies are urgently required. Comparisons between hospitals should help identify areas of inappropriate prescribing as well as effective drug use programs, but(More)
The lymphedema-lymphangiectasia-intellectual disability (Hennekam) syndrome (HS) is characterised by a widespread congenital lymph vessel dysplasia manifesting as congenital lymphedema of the limbs and intestinal lymphangiectasia, accompanied by unusual facial morphology, variable intellectual disabilities and infrequently malformations. The syndrome is(More)
3. Cohen MM Jr (1981) Overgrowth syndromes. In: Shafie MEL, Klippel CH (eds) Associated congenital anomalies. Williams and Wilkins, Baltimore 4. Cohen MM Jr (1982) The child with multiple birth defects. Raven Press, New York 5. Cordier MP, Robert JM, Malek R (1982) Un cas de magalosyndactylie. J Genet Hum 30 : 393-401 6. Greulich WW, Pyle SI (1966)(More)
In the week following a carnival during 19-24 February 1998, an outbreak of meningococcal disease occurred in a rural German county. The available isolates belonged to phenotype C:2a:P1.2,5 and were clonally related by pulsed-field gel electrophoresis. A case-control study was done to identify risk factors for the outbreak and to define possible vaccination(More)
We report the endophthalmitis rate after cataract surgery in patients preoperatively given topical povidone-iodine and gentamicin-containing irrigation fluid as prophylaxis without intracameral cefuroxime or perioperative topical antibiotics. In a retrospective clinical study, we included patients undergoing cataract surgery over a 12-year period at one(More)
Respiratory syncytial virus (RSV) usually causes self-limiting upper respiratory tract infections, but can be associated with severe lower respiratory tract infection disease (LRTID) in infants and in patients with hematologic malignancies. We have analyzed the risk factors and the measures for containment within an outbreak of nosocomial RSV infections in(More)
A 40-year-old woman with a history of a growing erythematous nodule in the umbilicus was diagnosed histopathologically with endometriosis. This umbilical endometriosis occurred spontaneously without any previous surgical procedures. The lesion was partially removed surgically; she then entered menopause with a spontaneous involution of the residuum during(More)
The Medical Device Amendments of 1976 define the increasingly important role of the FDA in the medical device manufacturer-user relationship. The new requirements imposed on the manufacturer, modifier and produce user must be implemented gradually. Guidance during this initial period is hard to come by, for many situations have not been clearly spelled out(More)