Umarkhon Azizov

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i. V. G. Kitaeva, N. M. Voronina, N. I. Latosh, at al., in: Organic Synthesis and Biological Activity [in Russian], Sverdlovsk (1978), p. 42. 2. V. G. Kitaeva, R. I. Ishmetova, I. I. Latosh, et el., in: Chemical Means of Plant Protection [in Russian], Ufa (1982), p. 35. 3. V. G. Kitaeva, R. Io Ishmetova, N. I. Latosh, and N. M. Voronina, Khim. Geterotsikl.(More)
In the title compound, C(14)H(16)N(6)O(6)·C(2)H(6)O·H(2)O, both substit-uents of the benzene ring are approximately planar with maximum deviations from the mean plane of 0.0561 (12) (an imine N atom) and 0.1419 (11) Å (a meth-oxy O atom). The substituents are tilted out of the plane of the benzene ring by 64.48 (4) and 70.08 (5)°, respectively. In the(More)
In the title molecule, C(24)H(15)Cl(4)N(3)O(4), the triazole ring makes dihedral angles of 72.02 (12), 81.60 (12) and 73.82 (11)°, respectively, with the adjacent phenyl ring and the two dichloro-benzene rings. In the crystal, a weak C-H⋯N inter-action, a short Cl⋯Cl contact [3.307 (2) Å] and a π-π stacking inter-action [centroid-centroid distance = 3.568(More)
Experiments on various animals showed that dichlotazole, a new triazole derivative, possesses a high antiinflammatory activity and low toxicity. The mechanism of the antiphlogistic effect of dichlotazol is due to its antagonism with respect to mediators of the inflammatory process and the ability of suppressing the increased permeability of capillaries.
By adding in one portion, half of the calculated amount of pure VII and a double amount of 10% KOH to a 1% aqueous solution of KMnO~ warmed to 45~ and holding the mixture for i0 min at this temperature, up to 50% of the keto acid II can be obtained, based on the phenylhydrazone isolated from the reaction products, of about 20% based on the preparatively(More)
2,3,5-Trimethylhydroquinone is an intermediate product in the production of vitamin E. The physiological action of vitamin E involves its participation in redox processes, wherein it protects lipid membranes from oxidation. Vitamin E is a blood coagulant, and influences the reproductive function. The absence of vitamin E in the organism leads to muscle(More)
Arctium lappa L. (Compositae) (burdock) is a large perennial herbaceous plant that has been known since antiquity for its useful properties [1]. Roots of burdock are used in folk medicine as a tincture, decoction, extract, and oil for gout, rheumatism, and several skin diseases and as a diuretic and pathogenic agent. It is used topically for eczema, ulcers,(More)
In continuation of our previous work devoted to the search for antiinflammatory agents among the derivatives of arylketocarboxylic acids [1 – 3], we have synthesized a series of new derivatives belonging to aromatic -ketocarboxylic acids and studied their antiinflammatory activity. The group of new compounds includes phenylhydrazone (I), thiosemicarbazone(More)
The literature records more than 50 methods of synthesis of PNAP and its modification, based on the use of two natural sources of raw material, benzene and toluene. On the whole, these methods may be divided into two groups: i) construction of the side chain of PNAP from the p-nitrobenzoyl moiety, and 2) introduction of the carbonyl group into an already(More)