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1. Simultaneous recordings of cortical activity, recorded as the magnetoencephalogram (MEG), and the electromyogram (EMG) of the ipsilateral and contralateral first dorsal interosseous muscles (1DI) were made during maintained voluntary contractions. 2. The MEG recorded from a localized region of the sensorimotor cortex of the dominant hemisphere was(More)
Stretching human muscles with a mechanical device gave rise to multiple peaks in the rectified and averaged electromyogram. In the first dorsal interosseous the latency of the first peak (M1) was 32.4 +/- 2.4 ms (SD) and the latency of the second peak (M2) was 55.1 +/- 11.3 ms, in both cases measured from the time of the stimulus to the take-off point of(More)
BACKGROUND Visual field defects are estimated to affect 20% to 57% of people who have had a stroke. Visual field defects can affect functional ability in activities of daily living (commonly affecting mobility, reading and driving), quality of life, ability to participate in rehabilitation, and depression, anxiety and social isolation following stroke.(More)
BACKGROUND In healthy people, rhythmic activation of the motor cortex in the 15-30 Hz frequency range accompanies and contributes to voluntarily-generated postural contractions of contralateral muscle. In patients with Parkinson's disease, an abnormal low-frequency activation of the motor areas of the cortex occurs and has been directly linked to the(More)
Continuously, moving objects under continuous illumination can be seen to move in a direction opposite to their actual motion. This illusory reversed motion can be explained as due to discrete temporal sampling of the moving stimulus by the visual system. If temporal sampling lies behind the illusory motion, then the probability of illusory motion should(More)
OBJECTIVE To establish the reliability of fetal magnetocardiography as a method of measuring the time intervals of the fetal heart during the antenatal period. DESIGN A prospective study. SETTING Wellcome Biomagnetism Unit, Southern General Hospital. SUBJECTS One hundred and six low risk pregnant women at 20 to 42 weeks gestation. MAIN OUTCOME(More)
The reflex activity of motoneurones to the extensor digitorum longus (EDL) muscle following sciatic nerve crush during the first 5 days after birth (neonatal crush) or in the adult (adult crush) was studied 3-6 months later, when the axons had reinnervated their target muscles. Electromyograms (EMG) and muscle tension were recorded from the EDL muscle (a(More)
After injury to the peripheral nerve in rat pups at 5 days of age the development of the fast muscles tibialis anterior and extensor digitorum longus is impaired. Whether the length of time during which the muscles are denervated affects the degree of impairment was studied here. In one group of animals the peroneal nerve was crushed near to the muscles in(More)
PURPOSE To examine absolute changes in oxygenated (HbO) and deoxygenated (Hb) hemoglobin concentrations over the visual cortex in response to visual stimulation. Before this study, only relative changes have been reported at the visual cortex. METHODS Near infrared spectroscopy (NIRS) can be used to assess changes in hemoglobin concentration in tissue. A(More)
PURPOSE The purpose of the study was to use functional near-infrared spectroscopy (fNIRS) to explore the extent of activation in occipito-parietal cortices to high-contrast checkerboard stimuli. The distributions of oxyhemoglobin (HbO), deoxyhemoglobin (Hb), and total hemoglobin (THb) concentrations were used as measures of cortical activation. METHODS(More)