Ulrike Kettenberger

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A good fixation of osteosynthesis implants is crucial for a successful bone healing but often difficult to achieve in osteoporotic patients. One possible solution to this issue is the local delivery of bisphosphonates in direct proximity to the implants, A critical aspect of this method, that has not yet been well investigated, is the time course of the(More)
Bisphosphonates are known for their strong inhibitory effect on bone resorption. Their influence on bone formation however is less clear. In this study we investigated the spatio-temporal effect of locally delivered Zoledronate on peri-implant bone formation and resorption in an ovariectomized rat femoral model. A cross-linked hyaluronic acid hydrogel was(More)
At the end of my life, I want to be able to tell a nice story! — from a friend This work is dedicated to Karolina and Norio. Acknowledgements I express my deep gratitude to my thesis director Prof. Christophe Moser and my co-supervisor Prof. Dominique Pioletti for the opportunity to conduct this research in their laboratories. I thank you for your patience,(More)
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