Ulrike G Schlüter

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BACKGROUND Matrix metalloproteinases (MMPs) are actively involved in the pathogenesis of Crohn's disease (CD). We assessed the effect of the anti-tumor necrosis factor-alpha (TNF-alpha) monoclonal antibody infliximab on the in vitro and in vivo expression of MMP-2 and MMP-9 in CD. METHODS Infliximab-treated fistulizing (n = 10) or active disease (n = 7)(More)
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