Ulrich Kruse

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1 Abstract—We carry out a sequence of numerical tests to understand conditions under which rapid changes in crustal thickness can be reliably imaged by teleseismic body waves. Using the finite-difference method over a 2-D grid, we compute synthetic seismograms resulting from a planar P-wavefield incident below the grid. We then image the Moho using a(More)
We describe a chemical proteomics approach to profile the interaction of small molecules with hundreds of endogenously expressed protein kinases and purine-binding proteins. This subproteome is captured by immobilized nonselective kinase inhibitors (kinobeads), and the bound proteins are quantified in parallel by mass spectrometry using isobaric tags for(More)
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