Ulrich Krüger

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In the 2009 European Guidelines on the diagnosis and treatment of pulmonary hypertension (PH), one section covers aspects of pathophysiology, diagnosis and treatment of chronic thromboembolic pulmonary hypertension (CTEPH). The practical implementation of the guidelines for this disease is of crucial importance, because CTEPH is a subset of PH which can(More)
This paper generalizes some aspects of polymatroid theory to partially ordered sets. The investigations are mainly based on Faigle and Kern, Submodular Linear Programs on Forests, Mathematical Programming 72 (1996). A slightly modiied concept of submodularity is introduced. As a consequence the main results do not require any assumptions concerning the(More)
Aim of the study was to evaluate whether late enhancement (LE) in contrast-enhanced MRI can be used to characterize fibrofatty myocardial replacement in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC). Fifteen patients with suspected ARVC underwent CE-MRI using a 1.5 T scanner. Long and short axis SSFP cine images and(More)
Systemic risk from financial intermediaries (FIs) refers to a negative externality problem which is rife with fallacy of composition type errors. To 'see' why seemingly rational behaviour at the level of an individual FI contributes to system wide instability is a non-trivial exercise which requires holistic visualization and modelling techniques. Paradox(More)
So-called epithelial rests of Malassez are derived from the Hertwig's root sheath and are located in the periodontal ligament, with still unknown functions. Different pathological conditions may lead to proliferation of these otherwise non-proliferative cell clusters. The insulin-like growth factor (IGF) system is an important growth factor system(More)
UNLABELLED No reliable data are available on cases of lethal child abuse (by active force) in the area of the former German Democratic Republic. In a multicenter study we therefore examined the police and court records for such cases occurring in the period 1 January 1985 to 2 October 1990 in the entire area of the former German Democratic Republic. (More)
BACKGROUND Subcutaneous treprostinil has dose-dependent beneficial effects in patients with severe pulmonary arterial hypertension, but adverse effects like infusion site pain can lead to treatment discontinuation. OBJECTIVES The objective of this study was to evaluate safety, tolerability and clinical effects of a rapid up-titration dosing regimen of(More)
UNLABELLED No reliable data are available on cases of lethal child neglect in the area of the former German Democratic Republic. In a multicenter study we therefore examined the police and court records for such cases occurring in the period 1 January 1985 to 2 October 1990 in the entire area of the former German Democratic Republic. RESULTS A total of 9(More)
Large epidemiological studies with over 5000 cases have the advantage of providing sufficient case numbers for the statistical evaluation of sub-groups. They are associated with a higher error rate in data collection and the influence of differences in judgment on part of the collaborators. In order to quantitatively assess these problems two studies were(More)