Ullrich Feine

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UNLABELLED We conducted a prospective study to define the sensitivity of 131I scintigraphy and 18FDG PET whole-body scanning in the detection of thyroid cancer and metastases. METHODS Forty-one patients with differentiated thyroid carcinoma who underwent thyroidectomy and 131I elimination of the remaining thyroid were studied by 18FDG whole-body PET in 52(More)
A prospective study of 106 orthopedic patients was performed for the detection of infection in the early postoperative stage using 99mTc-labeled murine Mabs directed against epitopes on granulocytes. Accuracy was 81% in the hips (n = 26), 81% in the thigh (n = 21), 84% in the knee (n = 19), and 100% in the tibia (n = 27). The technique did not work well in(More)
From 1984 to 1989, 47 children with relapsed, refractory, and/or metastasized neuroblastoma were treated with 131I-metaiodobenzylguanidine (mIBG) in several different treatment combinations. At initial diagnosis, 36 children had Evans stage IV and 11 stage III disease. In 16 of the 47 children, tumor recurred after complete remission prior to mIBG(More)
Our experience in scintigraphic diagnosis using 123I/131I-metaiodobenzylguanidine (MIBG) on 37 children with neuroblastomas stage III-IV is reported and discussed, together with the results obtained by other authors on MIBG diagnosis at the International Workshop of Pediatric Oncology held in Rome in September 1986. In our own investigation, 49 examinations(More)
BACKGROUND AND DESIGN A retrospective study involving 20 patients with melanoma with clinically suspicious lymph nodes was conducted to compare the diagnostic validity of fludeoxyglucose F 18 positron emission tomography (PET) and real-time ultrasonography in lymph node metastases of malignant melanoma. RESULTS A total of 83 lymph nodes were assessed with(More)
Due to their rarity, primary tumours of the pulmonary arteries are often incorrectly diagnosed as more common diseases such as pulmonary thromboembolism and are seldom diagnosed during a patient's lifetime. Surgery or potentially curative chemotherapy may therefore be withheld. We report a patient with a primary choriocarcinoma of the left pulmonary artery,(More)
A pharmacokinetic study was done to elucidate the body distribution, elimination, and metabolism of m-[131I]iodobenzylguanidine (m-[131I]IBG). For this purpose, an analytical method using solid phase extraction columns was developed. m-[131I]IBG was administered as an i.v. infusion according to different schedules with doses of 7,055 to 13,580 MBq/m2. At(More)
In 27 examinations of 24 patients with differentiated thyroid carcinoma an alternating pattern of metastases with either 131I- or FDG-uptake was found. In the follow-up of these patients this flip-flop pattern was seen in 89% (17/19) of patients with metastases and uptake of 131I or FDG as described here as uptake types 1 and 2 (type 1: FDG-positive and(More)