Ulla Vogel-Bindel

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1. The influence of the endogenous steroid epoxides 16 alpha, 17 alpha-epoxyestra-1,3,5(10)-trien-3-ol (estroxide) and 16 alpha, 17 alpha-expoxiandrost-4-en-3-one (androstene oxide) and their metabolic precursors estra-1,3,5(10), 16-tetraen-3-ol (estratetraenol) and androsta-4, 16-dien-3-one (androstadienone) on the specific activities of hepatic microsomal(More)
The specific activities of microsomal epoxide hydrolase with 16 alpha, 17 alpha-epoxyandrosten-3-one (androstene oxide) as substrate were measured in various metabolically important and in various steroidogenic organs of the male and female rat and compared with the activities of 16 alpha, 17 alpha-epoxyestratrienol (estroxide) and benzo[a]pyrene 4,5-oxide.(More)
Microsomal epoxide hydrolase, a major antigenic marker of putative preneoplastic hepatocytes was studied in hyperplastic liver nodules and in normal liver tissue. Hyperplastic nodules induced by two different protocols contained 2to 3-fold higher specific activities of microsomal epoxide hydrolase than did normal surrounding tissue. However, no increase in(More)
Microsomal epoxide hydrolase, a major antigenic marker of putative preneoplastic hepatocytes was studied in hyperplastic liver nodules and in normal liver tissue. Hyperplastic nodules induced by two different protocols contained 2to 3-fold higher specific activities of microsomal epoxide hydrolase than did normal surrounding tissue. However, no increase in(More)
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