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Advances in laboratory techniques have led to a rapidly increasing use of biomarkers in epidemiological studies. Biomarkers of internal dose, early biological change, susceptibility and clinical outcomes are used as proxies for investigating interactions between external and / or endogenous agents and body components or processes. The need for improved(More)
Introduction In recent years, advances in laboratory techniques have led to a rapidly increasing use of biomarkers in epidemiological studies, a field known as molecular epidemiology [1–5]. Biomarkers are any substance, structure or process that can be measured in biospecimens and may be associated with health-related outcomes. Biomarkers of internal dose,(More)
Rat ventral prostate and liver were investigated for the binding in vitro to particulate fractions and for the metabolism of 5 alpha-androstane-3 beta, 17 beta-diol. Comparative investigations were carried out on the metabolism of 5 alpha-androstane-3 alpha, 17 beta-diol. Preparations of the liver were investigated in order to establish the organ(More)
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