Ulf R Jensen-Kondering

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BACKGROUND AND PURPOSE We hypothesize that in acute middle cerebral artery stroke, thrombus lengths measured in thin-slice nonenhanced CT images define a limit beyond which systemic thrombolysis will fail to recanalize occluded arteries. METHODS In 138 patients who presented with acute middle cerebral artery stroke and who were treated with intravenous(More)
M apping the ischemic penumbra (ie, the neurophysio-logically silent but still viable ischemic tissue) is increasingly part of routine assessment in suspected acute stroke, although whether this approach is cost-effective is still unclear. 1,2 The penumbra is characterized by both low cerebral blood flow (CBF; Ͻ20 mL ⅐ 100 g Ϫ1 ⅐ min Ϫ1) and elevated oxygen(More)
There are two widely used transient middle cerebral artery occlusion (MCAO) methods, which differ in the use of unilateral or bilateral carotid artery reperfusion (UNICAR and BICAR). Of the two methods, UNICAR is easier to perform. This study was designed to comprehensively compare the two reperfusion methods to determine if there are any differences in(More)
OBJECTIVE Preoperative differentiation between primary central nervous system lymphoma (PCNSL) and high grade astrocytoma (HGA) on conventional magnetic resonance imaging (MRI) can be difficult and even impossible. However, differentiation is important to guide therapeutic strategy. Several authors have reported the leakage pattern in dynamic(More)
BACKGROUND AND PURPOSE As previously demonstrated, the recanalization rate and clinical outcome in patients with anterior circulation stroke treated with IV thrombolysis (IVT) depend on clot characteristics such as thrombus length and thrombus density. In patients with basilar artery occlusion (BAO) treated with IVT, the recanalization rate has also been(More)
INTRODUCTION AND OBJECTIVES Selective neuronal loss (SNL) in the reperfused penumbra may impact clinical recovery and is thus important to investigate. Brief proximal middle cerebral artery occlusion (MCAo) results in predominantly striatal SNL, yet cortical damage is more relevant given its behavioral implications and that thrombolytic therapy mainly(More)
OBJECTIVES It is well known that cerebral cavernous malformations (CCMs) present with variable degrees of contrast enhancement on routine magnetic resonance imaging (MRI) studies. This is attributed to the presence of a low flow vascular architecture in these lesions. The aim of this preliminary study was to determine whether an additional reason for the(More)
INTRODUCTION Spontaneous dissections of intracranial arteries are rare, but important causes of stroke, especially in younger patients. Dissections of the anterior cerebral artery (ACA) have been reported only very rarely in the European and North American populations but might be more prevalent than previously thought. METHODS This paper describes the(More)
INTRODUCTION Regarding therapy and prognosis of acute ischemic stroke the identification of ischemic penumbra is pivotal. A promising candidate is BOLD-imaging using qT2'-maps. For valid interpretation of experimental studies in animals normal values for qT2' are needed. Normal values in humans at 1.5T already exist. Normal values for cortical and(More)
Functional MRI (fMRI) is routinely used to depict language areas, for example in the preoperative diagnostic work-up of patients with a brain tumour. The objective of this study was to test whether semantic decision making can activate the temporo-parietal language areas better than phonological generation stimuli. Five fMRI language stimuli were tested in(More)