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BACKGROUND Cytological examination of effusion fluid is a relatively easy and quick method for the diagnosis of primary or secondary malignancy. AIMS To analyze the cytological significance of cell cannibalism in malignant effusion samples. MATERIALS AND METHODS A retrospective review of 100 cases of malignant effusion was done. These 100 cases included(More)
OBJECTIVE MicroRNAs (miRNAs) are short regulatory RNAs that can modulate gene expression and function as negative regulators. Common genetic variants like single nucleotide polymorphisms (SNPs) in miRNA genes may alter their expression or maturation resulting in varied functional consequences in carcinogenesis. Therefore, we evaluated the genetic variants(More)
BACKGROUND Fine needle aspiration (FNA) is a quick, minimally invasive procedure for evaluation of breast tumors. The Scarff-Bloom-Richardson (SBR) grade on histological sections is a well-established tool to guide selection of adjuvant systemic therapy. Grade evaluation is possible on cytology smears to avoid and minimize the morbidity associated with(More)
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