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Measurements of 5-FU Plasma Concentrations in Patients with Gastrointestinal Cancer: 5-FU Levels Reflect the 5-FU Dose Applied
With critical analysis of the measurements and correct performance of blood sampling, the measurement of 5-FU plasma concentrations with the immunoassay may in the future allow to optimize 4-FU dosing and to identify the cause of toxicity. Expand
Effect of free radical scavengers and metal ion chelators on hydrogen peroxide and phenylhydrazine induced red blood cell lipid peroxidation.
- H. Einsele, M. Clemens, U. Wegner, H. Waller
- Chemistry, Medicine
- Free radical research communications
Desferrioxamine a well-known iron chelator was found to decrease hydrogen peroxide and phenylhydrazine induced lipid peroxidation of red blood cell membranes assessed by hydrocarbon gas release and… Expand
Effect of the Antioxidant Idebenone on Adverse Events Under Mycophenolate Mofetil Therapy in a Rat Model
It can be hypothesized that enhanced EPO-mRNA expression in MMF/idebenone-treated rats is caused by antagonism of ROS, because ROS have the potential to suppress EPO expression. Expand
Measurement of 5-FU plasma levels in patients with advanced cancer: correct approach to practical procedures is essential.
[Hemolytic anemia caused by echinocytosis in liver cirrhosis].
Biochemical investigation of the lipid composition of the erythrocyte membrane and of plasma and of the apolipoproteins in plasma revealed a series of changes whose role in haemolysis is discussed. Expand
Measurements of 5-FU levels in plasma of patients with gastrointestinal cancer.
- M. Blaschke, S. Cameron, J. Blumberg, U. Wegner, G. Ramadori
- Journal of clinical oncology : official journal…
- 1 February 2012
Measurement of 5-FU plasma concentrations may in the future allow to optimize the5-FU dosing and to identify the cause of toxicity. Expand