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Sonic hedgehog is not required for the induction of medial floor plate cells in the zebrafish.
Sonic hedgehog (Shh) is a secreted protein that is involved in the organization and patterning of several tissues in vertebrates. We show that the zebrafish sonic-you (syu) gene, a member of a groupExpand
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Conserved and acquired features of adult neurogenesis in the zebrafish telencephalon.
Our understanding of the cellular and molecular mechanisms underlying the adult neural stem cell state remains fragmentary. To provide new models on this issue, we searched for stem cells in theExpand
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Neurogenesis in zebrafish – from embryo to adult
Neurogenesis in the developing central nervous system consists of the induction and proliferation of neural progenitor cells and their subsequent differentiation into mature neurons. External as wellExpand
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The activity of neurogenin1 is controlled by local cues in the zebrafish embryo.
Zebrafish neurogenin1 encodes a basic helix-loop-helix protein which shares structural and functional characteristics with proneural genes of Drosophila melanogaster. neurogenin1 is expressed in theExpand
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Dynamic microtubules and specification of the zebrafish embryonic axis
BACKGROUND The zebrafish is emerging as an important genetic system for the study of vertebrate development, and many zygotic mutations affecting embryogenesis have been isolated. The early events inExpand
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Axial, a zebrafish gene expressed along the developing body axis, shows altered expression in cyclops mutant embryos.
Here, we report the cloning of a cDNA from zebrafish encoding a member of the fork head/HNF3 gene family. The gene, which we have called Axial, begins to be expressed just before gastrulation in aExpand
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gfap and nestin reporter lines reveal characteristics of neural progenitors in the adult zebrafish brain
Adult neurogenesis arises from niches that harbor neural stem cells (NSC). Although holding great promise for regenerative medicine, the identity of NSC remains elusive. In mammals, a key attributeExpand
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Wnt5 is required for tail formation in the zebrafish embryo.
Intercellular signaling molecules, such as those encoded by the Wnt gene family, have a fundamental role in various aspects of pattern formation in the developing embryo. The zebrafish wnt5 geneExpand
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A crucial component of the endoderm formation pathway, CASANOVA, is encoded by a novel sox-related gene.
casanova (cas) mutant zebrafish embryos lack endoderm and develop cardia bifida. In a substractive screen for Nodal-responsive genes, we isolated an HMG box-containing gene, 10J3, which is expressedExpand
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Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo
The neurotransmitter acetylcholine (ACh) has a crucial role in central and neuromuscular synapses of the cholinergic system. After release into the synaptic cleft, ACh is rapidly degraded byExpand
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