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- Publications
- Influence
Modification of the fatty acid specificity of cytochrome P450 BM-3 from Bacillus megaterium by directed evolution: a validated assay
- Oliver Lentz, Qing-Shang Li, U. Schwaneberg, S. Lutz-Wahl, P. Fischer, R. Schmid
- Chemistry
- 1 November 2001
Cytochrome P450 BM-3 (CYP102) catalyzes the subterminal hydroxylation of fatty acids with a chain length of 12–22 carbons. The paper focuses on the regioselectivity and substrate specificity of the… Expand
Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450
- D. Lucas, Sophie Goulitquer, +5 authors L. Corcos
- Chemistry, Medicine
- Journal of Lipid Research
- 1 May 2010
Cytochromes P450 (CYPs) metabolize polyunsaturated long-chain fatty acids (PUFA-LC) to several classes of oxygenated metabolites. Through use of human recombinant CYPs, we recently showed that… Expand
Protein Engineering – An Option for Enzymatic Biofuel Cell Design
- G. Güven, Radivoje Prodanović, U. Schwaneberg
- Computer Science
- 1 April 2010
TLDR
Directed laccase evolution for improved ionic liquid resistance
- H. Liu, Leilei Zhu, M. Bocola, N. Chen, A. Spiess, U. Schwaneberg
- Chemistry
- 29 April 2013
In nature, the biodegradation of lignin is a challenging process since lignin is highly cross-linked and poorly water-soluble. Laccases (EC 1.10.3.2, benzenediol: oxygen oxidoreductase) play a key… Expand
Grafting PNIPAAm from β-barrel shaped transmembrane nanopores.
- Himanshu Charan, Julia Kinzel, +6 authors Alexander Böker
- Materials Science, Medicine
- Biomaterials
- 1 November 2016
The research on protein-polymer conjugates by grafting from the surface of proteins has gained significant interest in the last decade. While there are many studies with globular proteins, membrane… Expand
Structural Insight into Enantioselective Inversion of an Alcohol Dehydrogenase Reveals a "Polar Gate" in Stereorecognition of Diaryl Ketones.
- Jieyu Zhou, Y. Wang, +7 authors Ye Ni
- Chemistry
- 24 September 2018
Diaryl ketones are important building blocks for synthesizing pharmaceuticals and are generally regarded as “difficult-to-reduce” ketones due to the large steric hindrance of their two bulky aromatic… Expand
Ionic liquid effects on the activity of monooxygenase P450 BM-3
- K. L. Tee, D. Roccatano, S. Stolte, J. Arning, B. Jastorff, U. Schwaneberg
- Chemistry
- 3 January 2008
P450 monooxygenases oxidize a broad range of substrates including fatty acids, alcohols, aliphatic and aromatic hydrocarbons which are often poorly soluble in water and have Km values in the… Expand
In Vitro Double Oxidation of n-Heptane with Direct Cofactor Regeneration
- C. Müller, Beneeta Akkapurathu, +4 authors U. Schwaneberg
- Chemistry
- 17 June 2013
A novel concept for the direct oxidation of cycloalkanes to the corresponding cyclic ketones in a one-pot synthesis in water with molecular oxygen as sole oxidizing agent was reported recently. Based… Expand
A Whole Cell E. coli Display Platform for Artificial Metalloenzymes: Poly(phenylacetylene) Production with a Rhodium–Nitrobindin Metalloprotein
- A. R. Grimm, D. Sauer, +4 authors U. Schwaneberg
- Chemistry
- 21 February 2018
Whole cell catalysis is, in many cases, a prerequisite for the cost-effective production of chemicals by biotechnological means. Synthetic metal catalysts for bioorthogonal reactions can be… Expand
Prearranged glycosides, 2. Intramolecular glycosylation of prearranged saccharides as a novel strategy for the construction of β‐L‐rhamnosidic linkages
- R. Lau, G. Schüle, U. Schwaneberg, T. Ziegler
- Chemistry
- 1 October 1995
Disaccharides containing a β-L-rhamnosyl residue were prepared by a novel intramolecular glycosylation strategy. Thus, suitably benzyl-protected L-rhamnosyl donors (ethyl and phenyl 1-thiorhamnoside… Expand