Nutritional and toxicological importance of macro, trace, and ultra-trace elements in algae food products.
- C. Dawczynski, U. Schäfer, M. Leiterer, G. Jahreis
- Biology, MedicineJournal of Agricultural and Food Chemistry
- 10 November 2007
The content of 5 macro elements (Na, K, Ca, Mg, and P), 6 trace elements (Fe, Mn, Zn, Cu, Se, and I), and 4 ultra-trace elements (As, Pb, Cd, and Hg) in 34 edible dried seaweed products of brown algae and red algae originated from China, Japan and Korea and bought by retail in Germany was determined.
Size-Dependent Bioadhesion of Micro- and Nanoparticulate Carriers to the Inflamed Colonic Mucosa
The use of submicron-sized carriers holds promise for the targeted delivery of drugs to the inflamed colonic mucosal areas in inflammatory bowel disease.
Biodegradable nanoparticles for targeted drug delivery in treatment of inflammatory bowel disease.
The rolipram solution group had a high adverse effect index, whereas the ro Lipram nanoparticle groups proved their potential to retain the drug from systemic absorption as evidenced by a significantly reduced index.
Not ready to use – overcoming pitfalls when dispersing nanoparticles in physiological media
Beyond adsorption of proteins on metal oxide and polymeric nanoparticles, this work quantified nanoparticle deagglomeration due to adsorbing proteins acting as protection colloids and results in a checklist of pre-requirements for dispersion of nanoparticles in physiological media and for reliable attribution of potential toxic effects.
Selective follicular targeting by modification of the particle sizes.
Monolayers of Human Alveolar Epithelial Cells in Primary Culture for Pulmonary Absorption and Transport Studies
- K. Elbert, U. Schäfer, H. Schäfers, Kwang-Jin Kim, V. H. Lee, C. Lehr
- Biology, MedicinePharmaceutical Research
- 1 May 1999
A primary cell culture model of human alveolar epithelial cells has been established, which appears to be a valuable in vitro model for pulmonary drug delivery and transport studies.
Nortriptyline hydrochloride skin absorption: development of a transdermal patch.
Reconstructed epidermis versus human and animal skin in skin absorption studies.
The Use of Reconstructed Human Epidermis for Skin Absorption Testing: Results of the Validation Study
- M. Schäfer-Korting, U. Bock, M. Weimer
- Medicine, BiologyAlternatives to laboratory animals : ATLA
- 1 May 2008
The RHE models, EPISKIN, EpiDerm and SkinEthic, are appropriate alternatives to human and pig skin, for the in vitro assessment of the permeation and penetration of substances when applied as aqueous solutions.