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Astaxanthin, a carotenoid with potential in human health and nutrition.
- G. Hussein, U. Sankawa, H. Goto, Kinzo Matsumoto, Hiroshi Watanabe
- Medicine, BiologyJournal of natural products
In this review, the recent scientific literature is covered on the most significant activities of compound 1, including its antioxidative and anti-inflammatory properties, its effects on cancer, diabetes, the immune system, and ocular health, and other related aspects.
Identification of Claisen cyclase domain in fungal polyketide synthase WA, a naphthopyrone synthase of Aspergillus nidulans.
[Biosynthesis of plant pigments].
Cloning of the polyketide synthase gene atX from Aspergillus terreus and its identification as the 6-Methylsalicylic acid synthase gene by heterologous expression
- I. Fujii, Yuya Ono, H. Tada, K. Gomi, Y. Ebizuka, U. Sankawa
- BiologyMolecular and General Genetics MGG
- 27 November 1996
Abstract Southern blot analysis of genomic DNAs of several fungi that produce polyketide compounds with the 6-methylsalicylic acid synthase (MSAS) gene of Penicillium patulum as a probe indicated the…
Inhibition of prostaglandin and leukotriene biosynthesis by gingerols and diarylheptanoids.
- F. Kiuchi, S. Iwakami, M. Shibuya, F. Hanaoka, U. Sankawa
- Chemistry, BiologyChemical & pharmaceutical bulletin
- 25 February 1992
The rhizomes of Zingiber officinale (ginger) and Alpinia officinarum contain potent inhibitors against prostaglandin biosynthesizing enzyme (PG synthetase). Gingerols and diarylhepatanoids were…
Interaction of digitonin and its analogs with membrane cholesterol.
- M. Nishikawa, S. Nojima, T. Akiyama, U. Sankawa, K. Inoue
- Chemistry, BiologyJournal of biochemistry
- 1 October 1984
The interaction of digit onin with membrane cholesterol was studied by using various digitonin analogs, and radioactive desglucodigitonin, suggesting that the molecules could be inserted into the lipid bilayer free of cholesterol.
Re-identification of Aspergillus nidulans wA gene to code for a polyketide synthase of naphthopyrone
Antihypertensive and neuroprotective effects of astaxanthin in experimental animals.
The results indicate that astaxanthin can exert beneficial effects in protection against hypertension and stroke and in improving memory in vascular dementia.
Identification of amino acid residues important in the cyclization reactions of chalcone and stilbene synthases.
Results suggested that the G(372)FGPG loop in CHS and STS contribute to a determination of the outcome during cyclization reactions by serving as a part of the active-site scaffold on which the stereochemistry of cyclization is performed.
Degradation of ginseng saponins under mild acidic conditions.
The structures of the prosapogenins were investigated by (13)C-NMR spectroscopy and Rg (1)-prosapogenin II was shown to be a mixture of ginsenoside Rh (1), and its C-20 epimer, produced by hydrolysis followed by epimerization at C- 20.