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The germ cell nuclear factor mGCNF is expressed in the developing nervous system.
Using a reinoic acid receptor hybridization probe, we have isolated a mouse embryonic cDNA that encodes the germ cell nuclear factor (mGCNF). The in vitro translated protein binds specifically to theExpand
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Characterisation and differential expression of two very closely related G-protein-coupled receptors, GPR139 and GPR142, in mouse tissue and during mouse development
By searching the human and mouse genomic databases we found two G-protein-coupled receptors, GPR139 and GPR142, with characteristic motifs of the rhodopsin family of receptors. The gene for GPR139Expand
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The neuropeptide head activator is a high-affinity ligand for the orphan G-protein-coupled receptor GPR37
The neuropeptide head activator (HA) is a mitogen for mammalian cell lines of neuronal or neuroendocrine origin. HA signalling is mediated by a G-protein-coupled receptor (GPCR). Orphan GPCRs withExpand
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Differential expression of the estrogen receptor-related receptor γ in the mouse brain
To elucidate estrogen functions, the expression of the estrogen receptor-related receptor ERRγ, a novel orphan nuclear receptor regulating transcription via estrogen responsive elements, has beenExpand
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Retinoids Induce Differential Expression and DNA Binding of the Mouse Germ Cell Nuclear Factor in P19 Embryonal Carcinoma Cells
The mouse germ cell nuclear factor (GCNF), a member of the nuclear receptor superfamily, is highly expressed during gametogenesis and in the developing nervous system. The in vitro translated proteinExpand
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Unique expression pattern of a novel mosaic receptor in the developing cerebral cortex
Recently, a new type of transmembrane protein with a unique combination of protein domains was characterized from human, rabbit and chicken. This protein exhibits features of the low-densityExpand
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PGC-1 and PERC, coactivators of the estrogen receptor-related receptor gamma.
The mouse nuclear receptor ERRgamma (estrogen receptor-related receptor gamma) is highly expressed in heart, skeletal muscle, kidney, and brain, as well as in the developing nervous system. We foundExpand
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Domains of ERRgamma that mediate homodimerization and interaction with factors stimulating DNA binding.
The estrogen receptor-related receptor gamma (ERRgamma/ERR3/NR3B3) is an orphan member of the nuclear receptor superfamily closely related to the estrogen receptors. To explore the DNA bindingExpand
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Developmental expression of the estrogen receptor-related receptor γ in the nervous system during mouse embryogenesis
The ERR's (estrogen receptor-related receptors) are constitutive activators of the classical estrogen response element. In this report, we demonstrate that ERRgamma is highly expressed in the nervousExpand
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DNA binding, protein interaction and differential expression of the human germ cell nuclear factor.
The mouse germ cell nuclear factor (mGCNF) is an orphan nuclear receptor implicated in diverse biological processes, including gametogenesis, embryonic development and embryonal carcinoma cellExpand
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