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- Publications
- Influence
Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance
- R. Griffiths, W. A. Richards, U. McCann, R. Jesse
- Psychology, Medicine
- Psychopharmacology
- 7 July 2006
RationaleAlthough psilocybin has been used for centuries for religious purposes, little is known scientifically about its acute and persisting effects.ObjectivesThis double-blind study evaluated the… Expand
Memory impairment in abstinent MDMA ("Ecstasy") users
- K. Bolla, U. McCann, G. Ricaurte
- Psychology, Medicine
- Neurology
- 1 December 1998
Background: Methylenedioxymethamphetamine (MDMA, or "Ecstasy") is a popular recreational drug of abuse that is known to damage brain serotonergic neurons in animals and possibly humans. Few… Expand
Altered Serotonin Innervation Patterns in the Forebrain of Monkeys Treated with (±)3,4-Methylenedioxymethamphetamine Seven Years Previously: Factors Influencing Abnormal Recovery
- G. Hatzidimitriou, U. McCann, G. Ricaurte
- Psychology, Medicine
- The Journal of Neuroscience
- 15 June 1999
The recreational drug (±)3,4-methylenedioxymethamphetamine (MDMA, “Ecstasy”) is a potent and selective brain serotonin (5-HT) neurotoxin in animals and, possibly, in humans. The purpose of the… Expand
Psilocybin occasioned mystical-type experiences: immediate and persisting dose-related effects
- R. Griffiths, M. Johnson, W. A. Richards, Brian D Richards, U. McCann, R. Jesse
- Psychology, Medicine
- Psychopharmacology
- 15 June 2011
RationaleThis dose-effect study extends previous observations showing that psilocybin can occasion mystical-type experiences having persisting positive effects on attitudes, mood, and… Expand
(±)3,4-Methylenedioxymethamphetamine (‘Ecstasy’)-Induced Serotonin Neurotoxicity: Studies in Animals
- G. Ricaurte, J. Yuan, U. McCann
- Psychology, Medicine
- Neuropsychobiology
- 29 June 2000
The popular recreational drug, (±)3,4-methylenedioxymethamphetamine (MDMA; ‘Ecstasy’) is a potent and selective brain serotonin (5-HT) neurotoxin in animals. MDMA-induced 5-HT neurotoxicity can be… Expand
Serotonin Neurotoxicity after (±)3,4-Methylenedioxymethamphetamine (MDMA; “Ecstasy”): A Controlled Study in Humans
- U. McCann, A. Ridenour, Y. Shaham, G. Ricaurte
- Psychology, Medicine
- Neuropsychopharmacology
- 1 April 1994
(±)3,4-Methylenedioxymethamphetamine (MDMA; “Ecstasy”), an increasingly popular recreational drug, is known to damage brain serotonin 5-hydroxytryptamine (5-HT) neurons in experimental animals.… Expand
Reduced Striatal Dopamine Transporter Density in Abstinent Methamphetamine and Methcathinone Users: Evidence from Positron Emission Tomography Studies with [11C]WIN-35,428
- U. McCann, D. Wong, Fuji Yokoi, V. Villemagne, R. Dannals, G. Ricaurte
- Psychology, Medicine
- The Journal of Neuroscience
- 15 October 1998
Methamphetamine and methcathinone are psychostimulant drugs with high potential for abuse. In animals, methamphetamine and related drugs are known to damage brain dopamine (DA) neurons, and this… Expand
3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy"): pharmacology and toxicology in animals and humans.
- T. Steele, U. McCann, G. Ricaurte
- Psychology, Medicine
- Addiction
- 1 May 1994
(+/-)3,4-Methylenedioxymethamphetamine (MDMA, "Ecstasy"), a ring-substituted amphetamine derivative first synthesized in 1914, has emerged as a popular recreational drug of abuse over the last… Expand
The effects of sleep deprivation on pain inhibition and spontaneous pain in women.
- M. Smith, R. Edwards, U. McCann, J. Haythornthwaite
- Psychology, Medicine
- Sleep
- 1 April 2007
Impaired central pain modulation is implicated in the pathophysiology of chronic pain. In this controlled experiment, we evaluated whether partial sleep loss altered endogenous pain inhibition and… Expand
Cognitive performance in (±) 3,4-methylenedioxymethamphetamine (MDMA, “ecstasy”) users: a controlled study
- U. McCann, Melissa Mertl, Victoria Eligulashvili, G. Ricaurte
- Psychology, Medicine
- Psychopharmacology
- 1 April 1999
Rationale: (±) 3,4-Methylenedioxymethamphetamine (MDMA, “ecstasy”) is an amphetamine analog and drug of abuse. In animals, MDMA damages brain serotonin (5-HT) neurons at doses that overlap with those… Expand