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Intramedullary leg lengthening with a motorized nail
TLDR
Compared to external devices, intramedullary systems provide comfort and reduce complication rates, give improved cosmetic results, and lead to fast rehabilitation since percutaneous, transmuscular fixation is prevented, which results in reasonable overall treatment costs despite the relatively high costs of implants.
Prognostic factors and outcome of Liposarcoma patients: a retrospective evaluation over 15 years
TLDR
Grading, LS subtype, negative margins after surgery, metastases and tumour size are independently associated with disease-specific survival, and patients with local recurrence had lower survival rates.
Hyaluronic Acid Suppresses the Expression of Metalloproteinases in Osteoarthritic Cartilage Stimulated Simultaneously by Interleukin 1β and Mechanical Load
TLDR
The data suggest that under concurrent catabolic and anabolic stimulation, hyaluronic acid exhibits a pronounced suppressive effect on MMP-13, which may benefit the development of treatment strategies aimed at blocking tissue degradation in OA patients.
Percutaneous core needle biopsy versus open biopsy in diagnostics of bone and soft tissue sarcoma: a retrospective study
TLDR
In this study, moderately inferior results for the percutaneous biopsy technique compared to open biopsy in soft tissue tumours are found whereas almost equal results were obtained for both biopsy techniques for bone tumours.
Endoscopic resection and allografting for benign osteolytic lesions of the calcaneus
TLDR
Modifications to previously described techniques of endoscopic curettage with a particular focus on intraosseous lipoma are presented, finding that grafting with allogenic cancellous bone might prove favourable in this localization for several reasons.
The outcome of pelvic reconstruction with non-vascularised fibular grafts after resection of bone tumours.
TLDR
Non-vascularised fibular transfer to the pelvis is a simpler, cheaper and quicker procedure than other currently described techniques and is a biological reconstruction with good results and a relatively low donor site complication rate.
Non-vascularised fibula grafts for reconstruction of segmental and hemicortical bone defects following meta- /diaphyseal tumour resection at the extremities
TLDR
Non-vascularised fibula reconstructions should be considered a valuable alternative treatment option for patients with hemicortical defects or segmental reconstructions of less than 12 cm in which no additional neo-/adjuvant treatment is necessary.
Short- to long-term follow-up of total femoral replacement in non-oncologic patients
TLDR
Outcome of the patients in the present study did mainly depend on the age at reconstruction and not on the indication for TFR, which is a salvage procedure to restore mechanical integrity and regain functional ability after extensive femoral bone loss.
Diagnostic accuracy of arthroscopic biopsy in periprosthetic infections of the hip
BackgroundDiagnosis of a low-grade periprosthetic joint infection (PJI) prior to revision surgery can be challenging, despite paramount importance for further treatment. Arthroscopic biopsy of
PD-L1 and PD-1 and characterization of tumor-infiltrating lymphocytes in high grade sarcomas of soft tissue – prognostic implications and rationale for immunotherapy
TLDR
Findings represent novel insights into the immune landscape of soft tissue sarcomas, in particular UPS, and strengthen the rationale for immunotherapy, including targeting the PD-1/PD-L1 axis in these tumors.
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